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C2 (NM_013484) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210516L3V
- LentiORF®
-
Lenti ORF particles, C2 (Myc-DDK-tagged) - Mouse complement component 2 (within H-2S) (C2), 200ul, >10^7 TU/mL
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CNY 12,445.00
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Specifications
| Product Data | |
| Product Name | C2 (NM_013484) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_013484 |
| ORF Size | 2280 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210516).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_013484.1 |
| RefSeq Size | 2644 bp |
| RefSeq ORF | 2283 bp |
| Locus ID | 12263 |
| Gene Summary | This gene encodes component C2 of the classical pathway of the complement system. The encoded protein undergoes proteolytic processing mediated by component C1 resulting in C2a and C2b fragments. C2a fragment, in turn, selectively cleaves components C3 and C5 of the complement system. Mice lacking the encoded protein are found to be more susceptible to bacterial infections. Mutations in the human homolog of this gene are associated with disorders such as systemic lupus erythematosus, Henoch-Schonlein purpura, or polymyositis. [provided by RefSeq, Mar 2015] |
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