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Pla2g4a (NM_008869) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210449L4V
- LentiORF®
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Lenti ORF particles, Pla2g4a (GFP-tagged) - Mouse phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), 200ul, >10^7 TU/mL
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CNY 13,775.00
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规格
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Specifications
| Product Data | |
| Product Name | Pla2g4a (NM_008869) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | cP; cPL; cPLA2; cPLA2-alpha; cPLA2alpha; Pla; Pla2g4 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008869 |
| ORF Size | 2244 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210449).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008869.3 |
| RefSeq Size | 2846 bp |
| RefSeq ORF | 2247 bp |
| Locus ID | 18783 |
| Gene Summary | The protein encoded by this gene is a member of the phospholipase A2 group IV family. This enzyme hydrolyzes membrane phospholipids, thereby releasing the polyunsaturated fatty acid, arachidonic acid. Arachidonic acid is further metabolized into eicosanoids such as leukotrienes, thromboxanes and prostaglandins, that play important roles in regulating diverse biological processes such as inflammatory responses, membrane and actin dynamics, and tumorigenesis. A rise in intracellular calcium levels results in binding of calcium to the C2 domain of this protein, and triggers the translocation from the cytosol to intracellular membranes, including the Golgi apparatus. Disruption of this gene in mice led to decreased levels of eicosonaoids and platelet-activating factor, decreased allergic symptoms, and impaired reproductive ability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] |
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