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Ccnt2 (NM_028399) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210294L4V
- LentiORF®
-
Lenti ORF particles, Ccnt2 (GFP-tagged) - Mouse cyclin T2 (Ccnt2), 200ul, >10^7 TU/mL
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CNY 13,395.00
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Specifications
| Product Data | |
| Product Name | Ccnt2 (NM_028399) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2900041I18Rik; C81304; CycT2; CycT2a; CycT2b |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_028399 |
| ORF Size | 2169 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210294).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_028399.1, NP_082675.1 |
| RefSeq Size | 3514 bp |
| RefSeq ORF | 2172 bp |
| Locus ID | 72949 |
| Gene Summary | Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). The activity of this complex is regulated by binding with 7SK snRNA (By similarity). Plays a role during muscle differentiation; P-TEFB complex interacts with MYOD1; this tripartite complex promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation and binds the chromatin of promoters and enhancers of muscle-specific genes; this event correlates with hyperphosphorylation of the CTD domain of RNA pol II (PubMed:16245309, PubMed:23060074, PubMed:12037670). In addition, enhances MYOD1-dependent transcription through interaction with PKN1 (By similarity). Involved in early embryo development (PubMed:19364821).[UniProtKB/Swiss-Prot Function] |
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