Usp11 (NM_145628) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210123L4V
- LentiORF®
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Lenti ORF particles, Usp11 (GFP-tagged) - Mouse ubiquitin specific peptidase 11 (Usp11), 200ul, >10^7 TU/mL
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CNY 15,960.00
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Specifications
Product Data | |
Product Name | Usp11 (NM_145628) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 6230415D12Rik; mKIAA4085 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_145628 |
ORF Size | 2100 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210123).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145628.2 |
RefSeq Size | 3464 bp |
RefSeq ORF | 2766 bp |
Locus ID | 236733 |
Gene Summary | Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like complex.[UniProtKB/Swiss-Prot Function] |
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