Wwc1 (BC037006) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209954L4V
- LentiORF®
Lenti ORF particles, Wwc1 (GFP-tagged) - Mouse WW, C2 and coiled-coil domain containing 1 (cDNA clone MGC:47054 IMAGE:5116674), 200ul, >10^7 TU/mL
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CNY 13,205.00
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Specifications
Product Data | |
Product Name | Wwc1 (BC037006) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | MGC47054, mKIAA0869, RP23-196B5.5, Kibra |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | BC037006 |
ORF Size | 2025 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209954).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC037006, AAH37006 |
RefSeq Size | 2583 bp |
RefSeq ORF | 2027 bp |
Locus ID | 211652 |
Gene Summary | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ and may be associated with memory performance (By similarity). Regulates collagen-stimulated activation of the ERK/MAPK cascade.[UniProtKB/Swiss-Prot Function] |
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