Tnip1 (NM_021327) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209733L4V
- LentiORF®
-
Lenti ORF particles, Tnip1 (GFP-tagged) - Mouse TNFAIP3 interacting protein 1 (Tnip1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 12,540.00
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Tnip1 (NM_021327) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | ABIN; ABIN-1; ABIN1; AU018810; Naf1; Nef; VAN |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_021327 |
ORF Size | 1944 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209733).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021327.1, NP_067302.1 |
RefSeq Size | 2838 bp |
RefSeq ORF | 1944 bp |
Locus ID | 57783 |
Gene Summary | Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases.[UniProtKB/Swiss-Prot Function] |
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