Cnga3 (NM_009918) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209605L4V
- LentiORF®
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Lenti ORF particles, Cnga3 (GFP-tagged) - Mouse cyclic nucleotide gated channel alpha 3 (Cnga3), 200ul, >10^7 TU/mL
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CNY 12,255.00
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Specifications
Product Data | |
Product Name | Cnga3 (NM_009918) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | CNG3 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009918 |
ORF Size | 1893 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209605).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009918.1 |
RefSeq Size | 3512 bp |
RefSeq ORF | 1896 bp |
Locus ID | 12790 |
Gene Summary | Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones (By similarity). Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3.[UniProtKB/Swiss-Prot Function] |
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