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Kcna5 (NM_145983) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209320L4V
- LentiORF®
-
Lenti ORF particles, Kcna5 (GFP-tagged) - Mouse potassium voltage-gated channel, shaker-related subfamily, member 5 (Kcna5), 200ul, >10^7 TU/mL
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CNY 11,875.00
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Specifications
| Product Data | |
| Product Name | Kcna5 (NM_145983) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Kv1.5 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_145983 |
| ORF Size | 1809 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209320).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145983.1 |
| RefSeq Size | 3032 bp |
| RefSeq ORF | 1809 bp |
| Locus ID | 16493 |
| Gene Summary | Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:8226976, PubMed:11349004). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (By similarity). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (By similarity). Homotetrameric channels display rapid activation and slow inactivation (PubMed:8226976, PubMed:11349004). May play a role in regulating the secretion of insulin in normal pancreatic islets (By similarity).[UniProtKB/Swiss-Prot Function] |
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