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Grb7 (NM_010346) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208570L3V
- LentiORF®
-
Lenti ORF particles, Grb7 (Myc-DDK-tagged) - Mouse growth factor receptor bound protein 7 (Grb7), 200ul, >10^7 TU/mL
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CNY 9,880.00
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Specifications
| Product Data | |
| Product Name | Grb7 (NM_010346) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | mKIAA4028 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010346 |
| ORF Size | 1608 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208570).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010346.2, NP_034476.1 |
| RefSeq Size | 2413 bp |
| RefSeq ORF | 1608 bp |
| Locus ID | 14786 |
| Gene Summary | Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration (By similarity). Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.[UniProtKB/Swiss-Prot Function] |
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