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Ehd1 (NM_010119) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208555L3V
- LentiORF®
-
Lenti ORF particles, Ehd1 (Myc-DDK-tagged) - Mouse EH-domain containing 1 (Ehd1), 200ul, >10^7 TU/mL
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CNY 9,880.00
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Specifications
| Product Data | |
| Product Name | Ehd1 (NM_010119) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA409636; Past1; RME-1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010119 |
| ORF Size | 1602 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208555).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010119.5, NP_034249.1 |
| RefSeq Size | 3182 bp |
| RefSeq ORF | 1605 bp |
| Locus ID | 13660 |
| Gene Summary | ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (By similarity). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15930129, PubMed:20159556). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (PubMed:21177873). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (PubMed:24373286). Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (By similarity).[UniProtKB/Swiss-Prot Function] |
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