Kpna2 (BC003274) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208477L3V

  • LentiORF®

Lenti ORF particles, Kpna2 (Myc-DDK-tagged) - Mouse karyopherin (importin) alpha 2 (cDNA clone MGC:6031 IMAGE:3499880), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Kpna2 (BC003274) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2410044B12Rik; IPOA1; PTAC58; Rch1
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN BC003274
ORF Size 1587 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR208477).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC003274.1
RefSeq Size 1962 bp
RefSeq ORF 1589 bp
Locus ID 16647
Gene Summary Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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