Zc3hc1 (BC050141) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208050L4V
- LentiORF®
Lenti ORF particles, Zc3hc1 (GFP-tagged) - Mouse zinc finger, C3HC type 1 (cDNA clone MGC:60784 IMAGE:30011212), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
Product Data | |
Product Name | Zc3hc1 (BC050141) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1110054L24Rik; AU018540; AU019789; HSPC216; Nipa |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | BC050141 |
ORF Size | 1503 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208050).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC050141, AAH50141 |
RefSeq Size | 1819 bp |
RefSeq ORF | 1505 bp |
Locus ID | 232679 |
Gene Summary | Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (By similarity). Overexpression may be able to protect from apoptosis induced by IL-3 withdrawal.[UniProtKB/Swiss-Prot Function] |
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