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Txnip (BC011212) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206284L3V
- LentiORF®
-
Lenti ORF particles, Txnip (Myc-DDK-tagged) - Mouse thioredoxin interacting protein (cDNA clone MGC:18703 IMAGE:4193517), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Txnip (BC011212) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | THIF, VDUP1, mVDUP1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC011212 |
| ORF Size | 1200 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206284).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC011212, AAH11212 |
| RefSeq Size | 2799 bp |
| RefSeq ORF | 1202 bp |
| Locus ID | 56338 |
| Gene Summary | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.[UniProtKB/Swiss-Prot Function] |
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