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Tnfrsf10b (NM_020275) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR205945L3V
- LentiORF®
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Lenti ORF particles, Tnfrsf10b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Tnfrsf10b (NM_020275) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_020275 |
| ORF Size | 1143 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR205945).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_020275.3, NP_064671.2 |
| RefSeq Size | 3142 bp |
| RefSeq ORF | 1146 bp |
| Locus ID | 21933 |
| Gene Summary | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.[UniProtKB/Swiss-Prot Function] |
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