Hmgcl (NM_008254) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR204737L3V
- LentiORF®
Lenti ORF particles, Hmgcl (Myc-DDK-tagged) - Mouse 3-hydroxy-3-methylglutaryl-Coenzyme A lyase (Hmgcl), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Hmgcl (NM_008254) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AW476067; HL |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008254 |
ORF Size | 978 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204737).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008254.1 |
RefSeq Size | 1416 bp |
RefSeq ORF | 978 bp |
Locus ID | 15356 |
Gene Summary | Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.[UniProtKB/Swiss-Prot Function] |
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