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Alkbh3 (NM_026944) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR203896L4V
- LentiORF®
-
Lenti ORF particles, Alkbh3 (GFP-tagged) - Mouse alkB, alkylation repair homolog 3 (E. coli) (Alkbh3), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Alkbh3 (NM_026944) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1700108H04Rik; 1810020C19Rik; Abh3; mABH3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_026944 |
| ORF Size | 861 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR203896).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_026944.1, NP_081220.1 |
| RefSeq Size | 1247 bp |
| RefSeq ORF | 861 bp |
| Locus ID | 69113 |
| Gene Summary | Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (By similarity). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation (PubMed:16174769). Has a strong preference for single-stranded DNA (PubMed:16174769). Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons. Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).[UniProtKB/Swiss-Prot Function] |
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