March8 (Marchf8) (NM_027920) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203891L3V
- LentiORF®
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Lenti ORF particles, March8 (Myc-DDK-tagged) - Mouse membrane-associated ring finger (C3HC4) 8 (March8), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | March8 (Marchf8) (NM_027920) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1300017E09Rik; M; Marc; MARCH-VIII; March8; Mir |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_027920 |
ORF Size | 861 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203891).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_027920.4 |
RefSeq Size | 4521 bp |
RefSeq ORF | 861 bp |
Locus ID | 71779 |
Gene Summary | The protein encoded by this gene is a member of the membrane-associated really interesting new gene-CH family of proteins. These proteins are E3 ubiquitin-protein ligases that modulate antigen presentation by downregulating major histocompatibility complex class II surface expression through endocytosis. The transcript is primarily expressed by dendritic cells and macrophages. Overexpression of this gene in antigen presenting cells results in immune defective phenotypes, including resistance to autoimmune disease onset. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
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