Sirt3 (NM_001127351) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203304L4V
- LentiORF®
Lenti ORF particles, Sirt3 (GFP-tagged) - Mouse sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae) (Sirt3), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
Product Data | |
Product Name | Sirt3 (NM_001127351) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2310003L23Rik; AI848213; Sir2l3 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001127351 |
ORF Size | 774 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203304).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001127351.1, NP_001120823.1 |
RefSeq Size | 1439 bp |
RefSeq ORF | 774 bp |
Locus ID | 64384 |
Gene Summary | NAD-dependent protein deacetylase (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655). Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5PO (PubMed:16790548, PubMed:18794531, PubMed:21172655). Contributes to the regulation of the cellular energy metabolism (PubMed:23835326). Important for regulating tissue-specific ATP levels (PubMed:18794531, PubMed:24252090). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
You may also need
Customer
Reviews
Loading...