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Psmd10 (NM_016883) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202794L3V
- LentiORF®
-
Lenti ORF particles, Psmd10 (Myc-DDK-tagged) - Mouse proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (Psmd10), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Psmd10 (NM_016883) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AW554874 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_016883 |
| ORF Size | 696 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202794).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016883.3 |
| RefSeq Size | 1456 bp |
| RefSeq ORF | 696 bp |
| Locus ID | 53380 |
| Gene Summary | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module (By similarity). Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.[UniProtKB/Swiss-Prot Function] |
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