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Dkk4 (NM_145592) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202533L3V
- LentiORF®
-
Lenti ORF particles, Dkk4 (Myc-DDK-tagged) - Mouse dickkopf homolog 4 (Xenopus laevis) (Dkk4), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Dkk4 (NM_145592) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Dkk-4 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_145592 |
| ORF Size | 666 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202533).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145592.2 |
| RefSeq Size | 1315 bp |
| RefSeq ORF | 666 bp |
| Locus ID | 234130 |
| Gene Summary | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).[UniProtKB/Swiss-Prot Function] |
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