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Arl6 (NM_019665) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201738L4V
- LentiORF®
-
Lenti ORF particles, Arl6 (GFP-tagged) - Mouse ADP-ribosylation factor-like 6 (Arl6), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Arl6 (NM_019665) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110018H24Rik; 2210411E14Rik; BBS3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_019665 |
| ORF Size | 561 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201738).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_019665.2, NP_062639.2 |
| RefSeq Size | 1512 bp |
| RefSeq ORF | 561 bp |
| Locus ID | 56297 |
| Gene Summary | Involved in membrane protein trafficking at the base of the ciliary organelle (By similarity). Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (PubMed:24939912). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (By similarity). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (By similarity). Isoform 2 may be required for proper retinal function and organization (PubMed:20333246).[UniProtKB/Swiss-Prot Function] |
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