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Cd160 (NM_001163496) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201707L3V
- LentiORF®
-
Lenti ORF particles, Cd160 (Myc-DDK-tagged) - Mouse CD160 antigen (Cd160), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 6,650.00
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Specifications
| Product Data | |
| Product Name | Cd160 (NM_001163496) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AU045688; By55 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001163496 |
| ORF Size | 558 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201707).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001163496.1, NP_001156968.1 |
| RefSeq Size | 2590 bp |
| RefSeq ORF | 558 bp |
| Locus ID | 54215 |
| Gene Summary | CD160 antigen: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells (By similarity). Receptor for both classical and non-classical MHC class I molecules (PubMed:16177084). Receptor or ligand for TNF superfamily member TNFRSF14, participating in bidirectional cell-cell contact signaling between antigen presenting cells and lymphocytes. Upon ligation of TNFRSF14, provides stimulatory signal to NK cells enhancing IFNG production and anti-tumor immune response (PubMed:25711213). On activated CD4+ T cells, interacts with TNFRSF14 and downregulates CD28 costimulatory signaling, restricting memory and alloantigen-specific immune response (By similarity). In the context of bacterial infection, acts as a ligand for TNFRSF14 on epithelial cells, triggering the production of antimicrobial proteins and proinflammatory cytokines (PubMed:22801499).[UniProtKB/Swiss-Prot Function] |
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