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Nudt1 (NM_008637) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201165L3V
- LentiORF®
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Lenti ORF particles, Nudt1 (Myc-DDK-tagged) - Mouse nudix (nucleoside diphosphate linked moiety X)-type motif 1 (Nudt1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Nudt1 (NM_008637) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Mth1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_008637 |
| ORF Size | 471 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201165).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008637.1, NP_032663.1 |
| RefSeq Size | 939 bp |
| RefSeq ORF | 471 bp |
| Locus ID | 17766 |
| Gene Summary | Antimutagenic (PubMed:11572992). Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools (PubMed:29281266). Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP (By similarity). Does not play a role in U8 snoRNA decapping activity (PubMed:21070968). Binds U8 snoRNA (PubMed:21070968).[UniProtKB/Swiss-Prot Function] |
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