Psenen (NM_025498) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR200307L4V

  • LentiORF®

Lenti ORF particles, Psenen (GFP-tagged) - Mouse presenilin enhancer 2 homolog (C. elegans) (Psenen), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Psenen (NM_025498) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1700023M09Rik; Pen-2
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_025498
ORF Size 306 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR200307).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_025498.2
RefSeq Size 670 bp
RefSeq ORF 306 bp
Locus ID 66340
Gene Summary Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:12522139, PubMed:24941111). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:24941111).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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