United States
Germany
Japan
United Kingdom
China
Sem1 (NM_009169) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR200068L4V
- LentiORF®
-
Lenti ORF particles, Shfm1 (GFP-tagged) - Mouse split hand/foot malformation (ectrodactyly) type 1 (Shfm1), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Sem1 (NM_009169) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | DSS1; Shfdg1; Shfg; Shfm1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_009169 |
| ORF Size | 213 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR200068).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009169.1, NP_033195.1 |
| RefSeq Size | 491 bp |
| RefSeq ORF | 213 bp |
| Locus ID | 20422 |
| Gene Summary | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, SEM1, and either centrin CETN2 or CETN3. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and thus transcription-associated genomic instability. R-loop accumulation increases in SEM1-depleted cells.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
