AIP1 (MAGI2) (NM_001301128) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; NPHS15; SSCAM
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001301128, the custom clone sequence may differ by one or more nucleotides ATGTCCAAAAGCTTGAAAAAGAAAAGCCACTGGACTAGCAAAGTCCATGAGAGTGTCATTGGCAGGAACC CGGAGGGCCAGCTGGGCTTTGAACTGAAGGGGGGCGCCGAGAATGGACAGTTCCCCTACCTGGGGGAGGT GAAGCCCGGCAAGGTGGCCTATGAGAGCGGCAGCAAATTGGTGTCGGAGGAGCTGCTGCTGGAGGTGAAC GAGACCCCCGTGGCGGGGCTCACCATCAGGGACGTGCTGGCCGTGATCAAACACTGCAAGGACCCCCTCC GGCTCAAGTGTGTCAAGCAAGGAGGAATTGTTGATAAAGACCTTCGTCACTACCTCAACTTACGATTTCA AAAGGGTTCTGTGGACCATGAGCTTCAGCAAATCATTCGTGACAACCTCTACCTCCGCACGGTGCCATGC ACCACAAGGCCACATAAGGAGGGTGAGGTCCCTGGAGTGGATTATATTTTCATCACTGTTGAAGATTTTA TGGAATTGGAGAAAAGTGGTGCTCTCCTAGAAAGTGGGACTTATGAAGACAATTACTACGGTACCCCAAA GCCGCCAGCAGAACCAGCACCATTATTGTTAAATGTAACAGACCAGATACTTCCAGGAGCCACTCCAAGT GCTGAAGGAAAACGGAAGAGGAATAAATCAGTGAGCAACATGGAGAAAGCCAGTATAGAGCCTCCTGAGG AGGAAGAGGAAGAGAGGCCTGTGGTCAATGGAAATGGAGTAGTAGTAACACCAGAATCCAGTGAACATGA AGACAAAAGTGCAGGTGCCTCAGGGGAGATGCCCTCCCAGCCTTATCCTGCACCAGTGTACAGTCAGCCT GAGGAGCTGAAGGAGCAGATGGATGACACAAAGCCAACTAAACCTGAAGACAATGAGGAACCAGACCCAT TGCCTGATAACTGGGAAATGGCCTATACAGAGAAGGGCGAAGTCTACTTCATTGACCATAACACAAAGAC AACATCATGGCTGGATCCACGACTTGCGAAAAAGGCTAAACCTCCAGAAGAGTGCAAAGAAAATGAGCTT CCATATGGCTGGGAAAAAATCGATGATCCCATTTATGGCACTTATTATGTTGACCACATAAATAGAAGAA CACAGTTTGAAAATCCTGTCCTGGAAGCAAAAAGGAAGCTACAGCAACATAACATGCCCCACACAGAACT TGGAACAAAGCCCCTGCAGGCCCCAGGTTTCCGAGAAAAACCACTCTTCACCCGGGATGCATCCCAGTTG AAGGGAACATTCCTCAGCACCACCCTAAAAAAGAGCAACATGGGCTTTGGATTTACCATCATTGGTGGAG ACGAGCCTGATGAGTTTCTGCAGGTGAAAAGTGTGATTCCGGATGGGCCTGCAGCACAGGATGGAAAAAT GGAAACAGGTGATGTCATTGTCTATATTAATGAAGTTTGTGTCCTTGGACACACTCATGCAGATGTTGTC AAACTTTTCCAGTCTGTTCCTATTGGTCAGAGTGTCAACCTGGTGTTGTGTCGTGGCTACCCTTTGCCCT TTGATCCTGAAGACCCTGCTAACAGCATGGTGCCACCCCTTGCAATAATGGAGAGGCCACCTCCAGTGAT GGTCAATGGAAGACACAACTATGAAACATATTTGGAGTACATTTCTCGGACCTCACAGTCAGTTCCAGAT ATAACAGATCGGCCGCCTCATTCTCTGCACTCCATGCCAACTGATGGTCAGCTAGACGGCACGTATCCAC CGCCCGTCCATGATGACAATGTGTCTATGGCTTCATCTGGGGCCACCCAAGCTGAACTTATGACCTTAAC CATTGTGAAAGGTGCCCAGGGCTTCGGCTTCACTATTGCCGACAGTCCTACAGGACAGCGGGTGAAACAA ATACTTGACATTCAGGGATGCCCTGGCCTGTGTGAAGGCGACCTCATTGTTGAGATCAACCAGCAGAATG TACAGAACCTGAGCCATACAGAAGTAGTGGATATACTTAAGGACTGTCCCATTGGAAGTGAAACTTCTTT GATTATCCATCGAGGAGGTTTCTTTTCTCCATGGAAAACTCCAAAGCCTATAATGGACCGATGGGAGAAT CAAGGCAGTCCTCAAACGAGTTTATCTGCTCCGGCCATACCGCAGAACCTGCCCTTCCCACCTGCCCTTC ACAGGAGCTCCTTTCCTGACTCAACAGAGGCCTTTGACCCACGGAAGCCTGATCCATATGAGCTCTACGA GAAATCTAGGGCCATTTATGAAAGTAGGCGTCCAGATTATAAGGAATTGGATGTTCATCTTCGGAGGATG GAGTCTGGATTTGGCTTCAGAATCCTCGGGGGAGATGAGCCTGGACAGCCTATTTTGATTGGAGCTGTCA TTGCCATGGGCTCAGCCGACAGAGATGGCCGCCTTCACCCAGGAGATGAGCTTGTGTATGTTGATGGGAT TCCAGTAGCCGGCAAAACCCACCGCTATGTCATCGACCTCATGCACCACGCAGCCCGCAATGGGCAGGTC AACCTCACTGTGAGAAGAAAGGTGCTATGTGGAGGGGAGCCCTGCCCAGAGAACGGGAGAAGTCCAGGCT CTGTATCCACCCACCACAGCTCTCCACGCAGTGACTACGCAACCTACACCAACAGCAACCACGCTGCCCC CAGTAGCAATGCCTCTCCCCCTGAAGGCTTCGCCTCCCACAGCCTGCAGACCAGTGATGTGGTCATTCAC CGCAAAGAGAATGAGGGCTTCGGCTTTGTCATCATCAGCTCCCTGAACAGGCCTGAGTCTGGATCCACTA TAACTGTGCCCCATAAAATCGGACGCATCATTGATGGGAGTCCTGCAGATCGCTGTGCAAAACTAAAAGT GGGAGACCGGATCCTAGCAGTGAATGGCCAGTCTATCATCAACATGCCTCACGCTGACATCGTGAAGCTC ATCAAGGATGCAGGTCTTAGTGTCACCCTTCGCATCATTCCTCAGGAGGAGCTCAACAGCCCCACCTCGG CACCCAGCTCAGAGAAGCAGAGTCCCATGGCGCAGCAGAGTCCCCTGGCACAGCAGAGTCCCCTGGCCCA GCCAAGCCCAGCCACCCCCAACAGCCCCATCGCCCAGCCAGCACCACCTCAACCACTTCAGCTGCAAGGA CACGAAAATAGTTACAGGTCGGAAGTGAAAGCAAGGCAAGATGTGAAACCAGACATCCGACAGCCTCCAT TCACAGACTACAGGCAGCCCCCGCTGGATTACAGGCAACCCCCAGGAGGGGACTACCAGCAGCCCCCACC CTTGGACTACAGGCAGCCTCCCCTACTGGACTACAGGCAGCACTCCCCCGACACCAGGCAGTACCCTCTG TCGGACTACAGACAACCCCAGGATTTTGATTATTTCACTGTGGACATGGAGAAAGGAGCCAAAGGATTTG GATTCAGCATTCGTGGAGGAAGGGAATACAAAATGGATTTGTATGTGTTGAGACTGGCAGAAGATGGACC AGCAATAAGGAATGGGAGGATGAGGGTAGGAGATCAAATCATTGAAATCAATGGGGAAAGCACAAGGGAC ATGACACATGCCAGAGCAATAGAACTCATCAAATCTGGAGGAAGACGAGTGAGGCTGCTGCTCAAGAGAG GCACGGGACAGGTCCCAGAATATGACGAACCCGCCCCCTGGAGTTCTCCCGCTGCCGCCGCCCCAGGTCT GCCGGAAGTAGGCGTCTCCCTGGACGACGGCCTCGCTCCATTCTCTCCATCACATCCAGCCCCACCCTCC GACCCTTCCCACCAGATAAGCCCAGGCCCAACTTGGGATATCAAACGGGAACACGACGTTAGGAAACCAA AGGAGCTTTCAGCCTGCGGCCAGAAGAAGCAGCGCCTCGGGGAGCAGAGGGAGCGCTCGGCGAGTCCGCA GAGGGCCGCGCGGCCGAGGCTCGAGGAGGCGCCCGGCGGCCAGGGGCGGCCCGAGGCCGGCAGGCCCGCC TCGGAGGCCAGGGCGCCCGGGCTCGCGGCGGCAGACGCGGCGGACGCGGCGCGGGCGGGCGGGAAGGAGG CGCCCCGTGCGGCGGCGGGCTCCGAGCTCTGCCGGCGCGAAGGCCCGGGGGCTGCGCCGGCGTTTGCCGG CCCGGGCGGCGGCGGCAGCGGCGCGCTGGAGGCCGAGGGCAGGGCGGGTGCGCGCGCGGGTCCCCGGCCG GGCCCGCGACCCCCGGGGGGCGCCCCGGCGCGCAAGGCCGCCGTCGCGCCGGGGCCCTGGAAGGTGCCGG GTTCTGACAAGCTGCCCAGCGTCCTCAAACCCGGCGCCTCGGCCGCCAGCAGATGA
Restriction Sites	SgfI-MluI
ACCN	NM_001301128
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001301128.1, NP_001288057.1
RefSeq Size	6845 bp
RefSeq ORF	4326 bp
Locus ID	9863
UniProt ID	Q86UL8
Protein Families	Druggable Genome
Protein Pathways	Tight junction
Gene Summary	The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.