PIB5PA (INPP5J) (NM_001284286) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	INPP5; PIB5PA; PIPP
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001284286, the custom clone sequence may differ by one or more nucleotides ATGTCAGCTTCCTCGGAAGGACCGAGGCTGGCTCTGGCATCTCCCCGACCAATCCTGGCTCCACTGTGTA CCCCTGAAGGGCAGAAAACAGCTACTGCCCACCGCAGCTCCAGCCTGGCCCCAACATCTGTGGGCCAGCT GGTGATGTCTGCCTCAGCTGGACCAAAGCCTCCCCCAGCGACCACAGGCTCAGTTCTGGCTCCGACGTCC CTGGGGCTGGTGATGCCTGCCTCAGCAGGGCCAAGATCTCCCCCAGTCACCCTGGGGCCCAATCTGGCCC CAACCTCCAGAGACCAGAAGCAGGAGCCACCTGCCTCCGTGGGACCCAAGCCAACACTGGCAGCCTCTGG CCTGAGCCTGGCCCTGGCTTCTGAGGAGCAGCCCCCAGAACTCCCCTCCACCCCTTCCCCGGTGCCCAGT CCAGTTCTGTCTCCAACTCAGGAACAGGCCCTGGCTCCAGCATCCACGGCATCAGGCGCAGCCTCTGTGG GACAGACATCAGCTAGAAAGAGGGATGCCCCAGCCCCTAGACCTCTCCCTGCTTCTGAGGGGCATCTCCA GCCTCCAGCTCAGACATCTGGTCCTACAGGCTCCCCACCCTGCATCCAAACCTCCCCAGACCCTCGGCTC TCCCCCTCCTTCCGAGCCCGGCCTGAGGCCCTCCACAGCAGCCCTGAGGATCCTGTTTTGCCACGGCCAC CCCAGACCTTGCCCTTGGATGTGGGCCAGGGTCCTTCAGAGCCTGGCACTCACTCCCCTGGACTTCTGTC CCCCACCTTCCGGCCTGGGGCCCCCTCAGGCCAGACTGTGCCCCCACCTCTGCCCAAGCCACCCCGATCA CCCAGCCGTTCCCCAAGCCACTCCCCGAATCGCTCTCCCTGTGTTCCCCCAGCCCCTGACATGGCCCTCC CAAGGCTTGGCACACAGAGTACAGGGCCTGGCAGGTGCCTGAGCCCCAACCTTCAGGCCCAAGAAGCCCC AGCCCCAGTCACCACCTCCTCTTCTACATCCACCCTGTCATCCTCCCCTTGGTCAGCTCAGCCTACCTGG AAGAGCGACCCCGGCTTCCGGATCACTGTGGTCACATGGAACGTGGGCACTGCCATGCCCCCAGACGATG TCACATCCCTCCTCCACCTGGGCGGTGGTGACGACAGCGACGGCGCAGACATGATCGCCATAGGGTTGCA GGAAGTGAACTCCATGCTCAACAAGCGACTCAAGGACGCCCTCTTCACGGACCAGTGGAGTGAGCTGTTC ATGGATGCGCTAGGGCCCTTCAACTTCGTGCTGGTGAGTTCGGTGAGGATGCAGGGTGTCATCCTGCTGC TGTTCGCCAAGTACTACCACCTGCCCTTCCTGCGAGACGTGCAGACCGACTGCACGCGCACTGGCCTGGG CGGCTACTGGGGTAACAAGGGTGGCGTGAGCGTGCGCCTGGCGGCCTTCGGGCACATGCTCTGCTTCCTG AACTGCCACTTGCCTGCGCATATGGACAAGGCGGAGCAGCGCAAAGACAACTTCCAGACCATCCTCAGCC TCCAGCAGTTCCAAGGGCCGGGCGCACAGGGCATCCTGGATCATGACCTCGTGTTCTGGTTCGGGGACCT GAACTTCCGCATTGAGAGCTATGACCTGCACTTTGTCAAGTTTGCCATCGACAGTGACCAGCTCCATCAG CTCTGGGAGAAGGACCAGCTCAACATGGCCAAGAACACCTGGCCCATTCTGAAGGGCTTTCAGGAGGGGC CCCTCAACTTCGCTCCCACCTTCAAGTTTGATGTGGGTACCAACAAATACGATACCAGTGCCAAGAAACG GAAGCCAGCTTGGACAGACCGTATCCTATGGAAGGTCAAGGCTCCAGGTGGGGGTCCCAGCCCCTCAGGA CGGAAGAGCCACCGACTCCAGGTGACGCAGCACAGCTACCGCAGCCACATGGAATACACAGTCAGCGACC ACAAGCCTGTGGCTGCCCAGTTCCTCCTGCAGTTTGCCTTCAGGGACGACATGCCACTGGTGCGGCTGGA GGTGGCAGATGAGTGGGTGCGGCCCGAGCAGGCGGTGGTGAGGTACCGCATGGAAACAGTGTTCGCCCGC AGCTCCTGGGACTGGATCGGCTTATACCGGGTGGGTTTCCGCCATTGCAAGGACTATGTGGCTTATGTCT GGGCCAAACATGAAGATGTGGATGGGAATACCTACCAGGTAACATTCAGTGAGGAATCACTGCCCAAGGG CCATGGAGACTTCATCCTGGGCTACTATAGTCACAACCACAGCATCCTCATCGGCATCACTGAACCCTTC CAGATCTCGCTGCCTTCCTCGGAGTTGGCCAGCAGCAGCACAGACAGCTCAGGCACCAGCTCAGAGGGAG AGGATGACAGCACACTGGAGCTCCTTGCACCCAAGTCCCGCAGCCCCAGTCCTGGCAAGTCCAAGCGACA CCGCAGCCGCAGCCCGGGACTGGCCAGGTTCCCTGGGCTTGCCCTACGGCCCTCATCCCGTGAACGCCGT GGTGCCAGCCGTAGCCCCTCACCCCAGAGCCGCCGCCTGTCCCGAGTGGCTCCTGACAGGAGCAGTAATG GCAGCAGCCGGGGCAGTAGTGAAGAGGGGCCCTCTGGGTTGCCTGGCCCCTGGGCCTTCCCACCAGCTGT GCCTCGAAGCCTGGGCCTGTTGCCCGCCTTGCGCCTAGAGACTGTAGACCCTGGTGGTGGTGGCTCCTGG GGACCTGATCGGGAGGCCCTGGCGCCCAACAGCCTGTCTCCTAGTCCCCAGGGCCATCGGGGGCTGGAGG AAGGGGGCCTGGGGCCCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001284286
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001284286.1, NP_001271215.1
RefSeq Size	3529 bp
RefSeq ORF	2820 bp
Locus ID	27124
Protein Families	Druggable Genome
Protein Pathways	Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
Gene Summary	Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.

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