FBXL4 (NM_001278716) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	FBL4; FBL5; MTDPS13
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC337020 representing NM_001278716. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTCACCGGTCTTTCCCATGTTAACAGTTCTGACCATGTTTTATTATATATGCCTTCGGCGCCGAGCC AGGACAGCTACAAGAGGAGAAATGATGAACACCCATAGAGCTATAGAATCAAACAGCCAGACTTCCCCT CTCAATGCAGAGGTAGTCCAGTATGCCAAAGAAGTAGTGGATTTCAGTTCCCATTATGGAAGTGAGAAT AGTATGTCCTATACTATGTGGAATTTGGCTGGTGTACCAAATGTATTCCCAAGTTCTGGTGACTTTACT CAGACAGCTGTGTTTCGAACTTATGGGACATGGTGGGATCAGTGTCCTAGTGCTTCCTTGCCATTCAAG AGGACGCCACCTAATTTTCAGAGCCAGGACTATGTGGAACTTACTTTTGAACAACAGGTGTATCCTACA GCTGTACATGTTCTAGAAACCTATCATCCCGGAGCAGTCATTAGAATTCTCGCTTGTTCTGCAAATCCT TATTCCCCAAATCCACCAGCTGAAGTAAGATGGGAGATTCTTTGGTCAGAGAGACCTACGAAGGTGAAT GCTTCCCAAGCTCGCCAGTTTAAACCTTGTATTAAGCAGATAAATTTCCCCACAAATCTTATACGACTG GAAGTAAATAGTTCTCTTCTGGAATATTACACTGAATTAGATGCAGTTGTGCTACATGGTGTGAAGGAC AAGCCAGTGCTTTCTCTCAAGACTTCACTTATTGACATGAATGATATAGAAGATGATGCCTATGCAGAA AAGGATGGTTGTGGAATGGACAGTCTTAACAAAAAGTTTAGCAGTGCTGTCCTCGGGGAAGGGCCAAAT AATGGGTATTTTGATAAACTACCTTATGAGCTTATTCAGCTGATTCTGAATCATCTTACACTACCAGAC CTGTGTAGATTAGCACAGACTTGCAAACTACTGAGCCAGCATTGCTGTGATCCTCTGCAATACATCCAC CTCAATCTGCAACCATACTGGGCAAAACTAGATGACACTTCTCTGGAATTTCTACAGTCTCGCTGCACT CTTGTCCAGTGGCTTAATTTATCTTGGACTGGCAATAGAGGCTTCATCTCTGTTGCAGGATTTAGCAGG TTTCTGAAGGTTTGTGGATCCGAATTAGTACGCCTTGAATTGTCTTGCAGCCACTTTCTTAATGAAACT TGCTTAGAAGTTATTTCTGAGATGTGTCCAAATCTACAGGCCTTAAATCTCTCCTCCTGTGATAAGCTA CCACCTCAAGCTTTCAACCACATTGCCAAGTTATGCAGCCTTAAACGACTTGTTCTCTATCGAACAAAA GTAGAGCAAACAGCACTGCTCAGCATTTTGAACTTCTGTTCAGAGCTTCAGCACCTCAGTTTAGGCAGT TGTGTCATGATTGAAGACTATGATGTGATAGCTAGCATGATAGGAGCCAAGTGTAAAAAACTCCGGACC CTGGATCTGTGGAGATGTAAGAATATTACTGAGAATGGAATAGCAGAACTGGCTTCTGGGTGTCCACTA CTGGAGGAGCTTGACCTTGGCTGGTGCCCAACTCTGCAGAGCAGCACCGGGTGCTTCACCAGACTGGCA CACCAGCTCCCAAACTTGCAAAAACTCTTTCTTACAGCTAATAGATCTGTGTGTGACACAGACATTGAT GAATTGGCATGTAATTGTACCAGGTTACAGCAGCTGGACATATTAGGAACAAGAATGGTAAGTCCGGCA TCCTTAAGAAAACTCCTGGAATCTTGTAAAGATCTTTCTTTACTTGATGTGTCCTTCTGTTCGCAGATT GATAACAGAGCTGTGCTAGAACTGAATGCAAGCTTTCCAAAAGTGTTCATAAAAAAGAGCTTTACTCAG TGA
Restriction Sites	SgfI-MluI
ACCN	NM_001278716
Insert Size	1866 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001278716.1
RefSeq Size	2928 bp
RefSeq ORF	1866 bp
Locus ID	26235
UniProt ID	Q9UKA2
Protein Families	Druggable Genome
MW	70.1 kDa
Gene Summary	This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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