NKIAMRE (CDKL3) (NM_001300853) Human Untagged Clone
CAT#: SC335889
CDKL3 (untagged) - Human cyclin-dependent kinase-like 3 (CDKL3), transcript variant 3
CNY 3,800.00
货期*
3周
规格
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NKIAMRE |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC335889 representing NM_001300853.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGATCATTGAGATGGCCACTGGAAATCCCTATCTTCCTAGTAGTTCTGATTTGGATTTACTCCATAAA ATTGTTTTGAAAGTGGGCAATTTGTCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTTTTGCT GGGGTAGTTCTTCCTCAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGGATTG TTGGCAGATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTTTTG CATCATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAAGCTAAATTACTG CAGGAAGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAAGAAAATGAACTCAGGAAAGAT GAAAGAAAAACAGTTTATACCAATACACTGCTAAGTAGTTCAGTTTTGGGAAAGGAAATAGAAAAAGAG AAAAAGCCCAAGGAGATCAAAGTCAGAGTTATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCA AAAAAGAAAGAGTATGAAGGTGGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCA GATACAAAACTTGTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAA GAAAATCCACATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTGATGGCT GCAAATCTCAGTTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCAAAAAAGAGACGCACT TCTTCACAATCTATTGGACAAGTTATGCCTAATAGCAGGCAAGAGGATCCAGGTCCTATTCAAAGCCAA ATGGAGAAGGGTATATTTAATGAGCGAACAGGTCACAGTGACCAAATGGCAAATGAGAACAAAAGGAAG CTGAATTTTTCCAGATCTGACAGGAAAGAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAA GATACAAAAGGAATGGAAGTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCT AAGATACCAACTTTACTTAACGTGGATCAAAATCAAGAAAAACAAGAGAATACAGGAAATGCACAAACT GAAAGGAAGAAGAACTTGCCAGATGTAGAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001300853 |
Insert Size | 1206 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001300853.1 |
RefSeq Size | 1999 bp |
RefSeq ORF | 1206 bp |
Locus ID | 51265 |
UniProt ID | Q8IVW4 |
Protein Families | Druggable Genome, Protein Kinase |
MW | 45.1 kDa |
Gene Summary | The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) has an alternate 5' exon, which results in a different 5' UTR and translation initiation at a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. |
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