FMO2 (NM_001301347) Human Untagged Clone
CAT#: SC335285
FMO2 (untagged) - Human flavin containing monooxygenase 2 (non-functional) (FMO2), transcript variant 3
CNY 3,040.00
货期*
3周
规格
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | FMO1B1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC335285 representing NM_001301347.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTTTCGTTCTATGCTC CGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACAGATGAATCGGTGGTTCAACCAT GAAAATTATGGCCTTGAGCCTCAAAACAAATACATTATGAAGGAACCTGTACTAAATGATGATGTCCCA AGTCGTCTACTCTGTGGAGCCATCAAGGTGAAATCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATC TTTGAGGATGGAACAGTGGAGGAGAACATTGATGTCATCATTTTTGCAACAGGATATAGTTTCTCTTTT CCCTTCCTTGAAGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCC GCTCACCTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTTCCCAACT GCTGAACTTCAAGCTCGTTGGGTGACAAGAGTTTTCAAAGGCTTGTGTAGCCTGCCCTCAGAGAGAACT ATGATGATGGACATTATCAAAAGGAATGAAAAAAGAATTGACCTGTTTGGAGAAAGCCAGAGCCAGACG TTGCAGACCAATTATGTTGACTACTTGGACGAGCTCGCCTTAGAGATAGGTGCGAAGCCAGATTTCTGC TCTCTCTTGTTCAAAGATCCTAAACTGGCTGTGAGACTCTATTTCGGACCCTGCAACTCCTATCAGTAT CGCCTGGTTGGGCCTGGGCAATGGGAAGGAGCCAGAAATGCCATCTTCACCCAGAAACAAAGAATACTG AAGCCACTCAAGACTCGGGCCCTGAAGGATTCATCTAATTTCTCAGTTTCTTTTCTGTTGAAAATCCTG GGCCTTCTTGCTGTTGTTGTGGCCTTTTTTTGCCAACTTCAATGGTCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001301347 |
Insert Size | 948 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001301347.1 |
RefSeq Size | 5023 bp |
RefSeq ORF | 948 bp |
Locus ID | 2327 |
Protein Pathways | Drug metabolism - cytochrome P450 |
MW | 36.2 kDa |
Gene Summary | This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] Transcript Variant: This variant (3) lacks two alternate exons, and it thus differs in its 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. |
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