RBM38 (NM_001291780) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	dJ800J21.2; HSRNASEB; RNPC1; SEB4B; SEB4D
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001291780, the custom clone sequence may differ by one or more nucleotides ATGCTGCTGCAGCCCGCGCCGTGCGCCCCGAGCGCGGGCTTCCCGCGGCCCCTGGCCGCCCCCGGCGCCA TGCACGGCTCGCAGAAGGACACCACGTTCACCAAGATCTTCGTGGGCGGCCTGCCGTACCACACTACCGA CGCCTCGCTCAGGAAGTACTTCGAGGGCTTCGGCGACATCGAGGAGGCCGTGGTCATCACCGACCGCCAG ACGGGCAAGTCCCGCGGCTACGGCTTCGGGATTATTTTTGTCCTTGAAGGCCACATTTCCCAGGCCTTGA ACTTTGACGGGAGGAGCTGGAATCCAGGAGGCATCTTTGTGGGAGAGCCCCAGGTGACCATGGCCGACCG GGCGGCAGCTGAGAGGGCTTGCAAAGACCCGAACCCCATCATCGACGGCCGCAAGGCCAACGTGAACCTG GCATATCTGGGCGCCAAGCCGCGGAGCCTCCAGACGGGCTTTGCCATTGGGGTGCAGCAGCTGCACCCCA CCTTGATCCAGCGGACTTACGGGCTGACCCCGCACTACATCTACCCACCAGCCATCGTGCAGCCCAGCGT GGTGATCCCAGCCGCCCCTGTCCCGTCGCTGTCCTCGCCCTACATTGAGTACACGCCGGCCAGCCCGGCC TACGCCCAGTACCCACCGGCCACCTATGACCAGTACCCATACGCCGCCTCGCCTGCCACGGCTGCCAGCT TCGTGGGCTACAGCTACCCTGCCGCCGTGCCCCAGGCCCTCTCAGCCGCAGCACCCGCGGGCACCACTTT CGTGCAGTACCAGGCGCCGCAGCTGCAGCCTGACAGGATGCAGTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001291780
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001291780.1, NP_001278709.1
RefSeq Size	2506 bp
RefSeq ORF	816 bp
Locus ID	55544
UniProt ID	Q9H0Z9
Gene Summary	RNA-binding protein that specifically bind the 3' UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c).

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