hnRNP Q (SYNCRIP) (NM_001253771) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	GRY-RBP; GRYRBP; hnRNP-Q; HNRNPQ; HNRPQ1; NSAP1; PP68
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332223 representing NM_001253771. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGAGGACCACCTCCAGATTCCGTTTATTCAGATATTTGTGGGAAAGATCCCAAGAGATCTATTTGAG GATGAACTTGTTCCATTATTTGAGAAAGCTGGACCTATATGGGATCTTCGTCTAATGATGGATCCACTC ACTGGTCTCAATAGAGGTTATGCGTTTGTCACTTTTTGTACAAAAGAAGCAGCTCAGGAGGCTGTTAAA CTGTATAATAATCATGAAATTCGTTCTGGAAAACATATTGGTGTCTGCATCTCAGTTGCCAACAATAGG CTTTTTGTGGGCTCTATTCCTAAGAGTAAAACCAAGGAACAGATTCTTGAAGAATTTAGCAAAGTAACA GAGGGTCTTACAGACGTCATTTTATACCACCAACCGGATGACAAGAAAAAAAACAGAGGCTTTTGCTTT CTTGAATATGAAGATCACAAAACAGCTGCCCAGGCAAGGCGTAGGTTAATGAGTGGTAAAGTCAAGGTC TGGGGGAATGTTGGAACTGTTGAATGGGCTGATCCTATAGAAGATCCTGATCCTGAGGTTATGGCAAAG GTAAAAGTGCTGTTTGTACGCAACCTTGCCAATACTGTAACAGAAGAGATTTTAGAAAAGGCATTTAGT CAGTTTGGGAAACTGGAACGAGTGAAGAAGTTAAAAGATTATGCGTTCATTCATTTTGATGAGCGAGAT GGTGCTGTCAAGGCTATGGAAGAAATGAATGGCAAAGACTTGGAGGGAGAAAATATTGAAATTGTTTTT GCCAAGCCACCAGATCAGAAAAGGAAAGAAAGAAAAGCTCAGAGGCAAGCAGCAAAAAATCAAATGTAT GACGATTACTACTATTATGGTCCACCTCATATGCCCCCTCCAACAAGAGGTCGAGGGCGTGGAGGTAGA GGTGGTTATGGATATCCTCCAGATTATTATGGATATGAAGATTATTATGATTATTATGGTTATGATTAC CATAACTATCGTGGTGGATATGAAGATCCATACTATGGTTATGAAGATTTTCAAGTTGGAGCTAGAGGA AGGGGTGGTAGAGGAGCAAGGGGTGCTGCTCCATCCAGAGGTCGTGGGGCTGCTCCTCCCCGCGGTAGA GCCGGTTATTCACAGAGAGGAGGTCCTGGATCAGCAAGAGGCGTTCGAGGTGCGAGAGGAGGTGCCCAA CAACAAAGAGGCCGCGGGCAGGGAAAAGGGGTCGAGGCCGGTCCTGACCTGTTACAATGA
Restriction Sites	SgfI-MluI
ACCN	NM_001253771
Insert Size	1233 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001253771.1
RefSeq Size	6716 bp
RefSeq ORF	1233 bp
Locus ID	10492
UniProt ID	O60506
Protein Families	Stem cell - Pluripotency
MW	46.3 kDa
Gene Summary	This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (7) differs in the 3' UTR, lacks an internal exon, uses an alternate splice site in the coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (7) is shorter and has distinct N- and C-termini, compared to isoform 1.

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