Synphilin 1 (SNCAIP) (NM_001242935) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	Sph1; SYPH1
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331932 representing NM_001242935. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGACATATCTTATTCAGTCACATCACTCAAGACGATCCCAGAACTGTGCCGAAGATGTGATACGCAAA ACGAAGACAGATCAGAATGGTCAGTTGGAGTGCGTACGCTGGATGGTGAGCGAAACAGAAGCCATTGCA GAACTGAGTTGTTCTAAGGATTTTCCAAGCCTTATTCATTACGCAGGTTGCTATGGCCAGGAAAAGATT CTTCTGTGGCTTCTTCAGTTTATGCAAGAACAGGGCATCTCGTTGGATGAAGTAGACCAGGATGGCAAC AGTGCCGTTCACGTAGCCTCACAGCATGGCTACCTTGGATGCATACAGACCTTGGTTGAATATGGAGCA AATGTCACCATGCAGAACCACGCTGGGGAAAAGCCCTCCCAGAGCGCCGAGCGGCAGGGGCACACCCTG TGCTCCAGGTACCTGGTGGTGGTGGAGACCTGCATGTCGCTGGCCTCTCAAGTGGTGAAGTTAACCAAG CAGCTAAAGGAACAAACAGTAGAACGTGTCACGCTGCAGAACCAACTCCAACAATTTCTAGAAGCCCAG AAATCAGAGGGCAAGTCACTCCCTTCTTCACCCAGTTCACCATCCTCACCTGCCTCCAGAAAGTCCCAG TGGAAATCTCCAGATGCAGATGATGATTCTGTAGCCAAAAGCAAGCCAGGAGTCCAAGAGGGGATTCAG GTTCTTGGAAGCCTGTCAGCCTCCAGCCGGGCTAGACCCAAAGCAAAAGATGAAGATTCTGATAAAATC TTACGCCAGTTATTGGGAAAGGAAATCTCAGAAAATGTCTGCACCCAGGAAAAACTGTCCTTGGAATTC CAGGATGCTCAGGCTTCCTCTAGAAATTCTAAAAAGATCCCACTGGAGAAGAGGGAACTGAAGTTAGCC AGGCTGAGACAGCTGATGCAGAGGTCACTGAGTGAGTCTGACACAGACTCCAACAACTCTGAGGACCCC AAGACTACCCCAGTGAGGAAGGCTGACCGACCAAGGCCGCAGCCCATTGTAGAAAGCGTAGAGAGTATG GACAGCGCAGAAAGCCTGCACCTGATGATTAAGAAACACACCTTGGCATCAGGGGGACGCAGGTTTCCT TTCAGCATCAAGGCCTCCAAATCCCTGGATGGCCACAGCCCATCTCCCACCTCAGAGAGCAGCGAACCA GACTTAGAATCCCAGTATCCAGGCTCAGGGAGTATTCCTCCAAACCAGCCCTCTGGTGACCCTCAGCAG CCCAGCCCTGACAGTACTGCTGCCCAGAAAGTTGCCACAAGTCCCAAGAGTGCCCTCAAGTCTCCATCT TCCAAGCGTAGGACATCTCAGAACTTAAAACTGAGAGTTACCTTTGAGGAGCCTGTGGTGCAGATGGAG CAGCCTAGCCTTGAACTGAATGGAGAAAAAGACAAAGATAAGGGCAGGACTCTCCAGCGGACCTCCACA AGTAACGAATCGGGGGATCAACTGAAAAGGCCTTTTGGAGCCTTTCGATCTATCATGGAGACACTAAGT GGCAACCAAAACAATAATAATAACTACCAGGCAGCCAACCAGCTGAAAACCTCTACATTGCCCTTGACC TCACTTGGGAGGAAGACAGATGCCAAGGGAAACCCTGCCAGCTCCGCTAGCAAAGGAAAGAATAAGGCA GAAATGTACAGCAGCTGCATCAATCTTTCCTCTAACATGCTGATTGAAGAGCATCTGTGTAACGACACA CGGCATAATGACATCAATAGAAAAATGAAGAAATCCTACAGCATAAAGCACATTGCTGAGCCAGAGTCA AAAGAACTCTTCTTGTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001242935
Insert Size	1812 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001242935.1
RefSeq Size	2588 bp
RefSeq ORF	1812 bp
Locus ID	9627
UniProt ID	Q9Y6H5
Protein Pathways	Parkinson's disease
MW	66.6 kDa
Gene Summary	This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (1A) differs in the 5' UTR, lacks an alternate exon in the 5' coding region that results in translation initiation from a downstream start codon in a different reading frame, and lacks two alternate exons in the central coding region, compared to variant 2. The encoded isoform (1A) has a distinct N-terminus and is shorter than isoform 2.

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