SORCS1 (NM_001206572) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	hSorCS
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331661 representing NM_001206572. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGGAAAAGTTGGCGCCGGCGGCGGCTCCCAAGCCCGGCTGAGCGCGCTCCTCGCCGGCGCGGGGCTC TTGATCCTCTGCGCCCCGGGCGTCTGCGGCGGCGGCTCCTGCTGCCCCTCGCCGCACCCCAGCTCCGCT CCACGCTCGGCCTCGACCCCTAGGGGCTTTTCCCACCAGGGGCGGCCAGGCAGGGCTCCTGCCACGCCC CTGCCCCTCGTAGTGCGTCCCCTGTTCTCAGTGGCCCCCGGGGACCGAGCGCTATCCCTGGAGCGGGCT CGGGGCACTGGGGCATCCATGGCGGTTGCTGCACGCTCCGGCCGGAGGAGACGGAGCGGAGCGGATCAG GAGAAGGCAGAACGGGGAGAGGGCGCGAGTCGGAGCCCCCGGGGAGTGCTAAGAGATGGAGGGCAGCAG GAGCCTGGGACTCGGGAGCGGGACCCGGACAAAGCCACCCGCTTCCGGATGGAGGAGCTGAGACTGACC AGCACCACGTTTGCGCTGACGGGAGACTCAGCACACAACCAAGCCATGGTCCACTGGTCTGGCCACAAC AGCAGCGTGATTCTCATTTTGACAAAGCTCTATGACTATAACCTGGGGAGCATCACAGAGAGCTCGCTT TGGAGGTCAACCGATTATGGAACAACCTATGAGAAGCTGAATGATAAAGTTGGTTTGAAAACCATTTTG AGCTATCTCTATGTGTGTCCTACCAACAAGCGTAAGATAATGTTACTCACAGACCCGGAGATTGAGAGC AGTTTATTGATCAGCTCAGATGAAGGGGCAACTTATCAAAAGTACCGGCTGAACTTCTACATTCAAAGC TTGCTTTTTCACCCCAAACAAGAAGACTGGATTCTGGCATACAGTCAAGACCAAAAGTTATACAGCTCT GCTGAATTTGGGAGAAGATGGCAGCTTATCCAAGAAGGGGTTGTACCAAACAGGTTCTACTGGTCTGTG ATGGGGTCAAATAAAGAACCAGACCTTGTGCATCTTGAGGCCAGAACTGTGGATGGTCATTCACATTAT CTAACTTGCCGAATGCAGAACTGTACAGAGGCCAACAGGAATCAGCCTTTTCCAGGCTACATTGACCCA GACTCTTTGATTGTTCAGGATCATTATGTGTTTGTTCAGCTGACATCAGGAGGGCGGCCACATTACTAC GTGTCCTACCGAAGGAATGCATTTGCCCAAATGAAGCTTCCGAAATATGCTTTGCCCAAGGACATGCAT GTTATCAGCACCGATGAGAATCAGGTGTTCGCAGCGGTCCAAGAATGGAACCAGAATGACACGTACAAC CTCTACATCTCAGACACACGTGGTGTCTACTTCACCCTGGCCTTGGAGAATGTCCAGAGCAGCAGAGGC CCTGAGGGCAACATCATGATCGACCTCTATGAGGTAGCAGGGATAAAGGGAATGTTCTTGGCTAACAAG AAGATTGACAACCAAGTGAAGACTTTCATCACATATAACAAAGGCAGAGACTGGCGTTTGCTGCAGGCG CCGGACACGGATCTAAGGGGGGACCCCGTGCACTGCTTGCTGCCCTATTGCTCACTACACCTTCACCTG AAGGTCTCTGAGAATCCCTACACATCAGGGATCATTGCCAGCAAAGACACAGCTCCAAGCATCATAGTG GCATCAGGTAATATAGGTTCTGAATTGTCAGACACTGACATCAGCATGTTTGTCTCTTCAGATGCAGGG AACACCTGGAGACAGATCTTTGAAGAAGAGCACAGTGTTTTGTACCTGGATCAAGGTGGAGTCCTGGTT GCTATGAAACACACATCTCTCCCAATTCGACATCTTTGGTTGAGTTTTGATGAAGGGAGATCTTGGAGC AAATACAGTTTCACATCTATTCCACTTTTTGTGGATGGGGTTCTGGGTGAGCCTGGAGAAGAGACTCTC ATCATGACAGTGTTTGGACACTTCAGCCACCGCTCTGAATGGCAGCTGGTCAAAGTAGATTACAAGTCC ATTTTTGATAGACGGTGTGCCGAAGAGGACTACAGACCTTGGCAGCTGCACAGCCAGGGGGAAGCATGT ATCATGGGAGCAAAAAGGATATATAAGAAGCGAAAATCAGAGCGGAAGTGTATGCAAGGAAAATATGCA GGAGCTATGGAATCTGAACCCTGTGTCTGCACTGAGGCTGATTTTGATTGCGACTATGGTTATGAGCGA CACAGCAATGGCCAGTGCCTGCCGGCATTTTGGTTCAATCCATCCTCTCTGTCAAAGGATTGCAGCTTG GGACAGAGTTACCTCAATAGTACTGGGTACAGGAAGGTGGTTTCCAATAATTGCACTGATGGCGTAAGG GAACAGTACACTGCCAAACCGCAGAAGTGCCCAGGGAAAGCCCCGCGGGGGCTGCGGATAGTCACGGCT GATGGAAAGCTGACAGCGGAACAAGGACACAACGTCACTCTCATGGTGCAATTAGAAGAGGGTGATGTT CAGCGGACACTCATCCAAGTGGACTTTGGCGATGGTATCGCGGTGTCTTACGTCAATCTCAGCTCCATG GAAGATGGGATCAAACACGTCTATCAGAACGTGGGCATTTTCCGTGTGACCGTGCAGGTGGACAACAGT CTGGGTTCTGACAGCGCCGTCCTGTACTTACATGTAACTTGTCCCTTGGAGCACGTGCACCTGTCTCTT CCCTTTGTCACCACAAAGAACAAAGAGGTCAATGCGACGGCAGTGCTGTGGCCCAGCCAAGTGGGCACC CTCACTTACGTGTGGTGGTACGGAAACAACACGGAGCCTTTGATCACCTTGGAGGGAAGCATATCCTTC AGATTTACTTCAGAAGGAATGAATACCATCACAGTGCAGGTCTCAGCTGGGAATGCCATCCTACAAGAC ACAAAGACCATCGCAGTATATGAGGAATTCCGGTCTCTTCGCTTGTCCTTTTCTCCAAACCTGGATGAC TACAACCCGGACATCCCTGAGTGGAGGAGGGACATCGGTCGAGTCATCAAAAAATCCCTGGTGGAAGCC ACAGGGGTTCCAGGCCAGCACATCCTGGTGGCGGTGCTCCCTGGCTTACCCACCACTGCTGAACTCTTT GTCCTACCCTATCAGGATCCAGCTGGAGAAAACAAAAGGTCAACTGATGACCTGGAGCAGATATCAGAA TTGCTGATCCACACGCTCAACCAAAACTCAGTACACTTCGAGCTGAAGCCAGGAGTCCGAGTCCTTGTC CATGCTGCTCACTTAACAGCGGCCCCCCTGGTGGACCTCACTCCAACCCACAGTGGATCTGCCATGCTG ATGCTGCTCTCAGTGGTGTTTGTGGGGCTGGCAGTGTTCGTCATCTACAAGTTTAAAAGGAAGATCCCG GGGATTAATGTTTATGCCCAGATGCAGAATGAGAAAGAACAAGAGATGATCAGTCCAGTCAGTCACTCT GAAAGCAGGCCCAATGTCCCTCAGACTGAACTAAGGAGGCCTGGCCAGCTTATAGATGAGAAGGTGGAA TCCCAGCTCATAGGAGAGTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001206572
Insert Size	3540 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001206572.1
RefSeq Size	7623 bp
RefSeq ORF	3540 bp
Locus ID	114815
UniProt ID	Q8WY21
Protein Families	Druggable Genome, Transmembrane
MW	131.3 kDa
Gene Summary	This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (6) differs in the 3' UTR and coding sequence compared to variant 2. The resulting isoform (f) has a shorter and distinct C-terminus compared to isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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