ZNF568 (NM_001204839) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ZFP568
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331620 representing NM_001204839. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGAAACCTGCTCAAAGAAACTTGTATCGAGATGTGATGCTGGAGAACTACAGCAACCTAGTCACAGTG GGCTGTCAAGTCACCAAACCGGATGTGATATTCAAGTTGGAGCAAGAAGAGGAGCCCTGGGTGATGGAG GAAGAAATGTTTGGGAGGCACTGTCCAGAACCCAGAAGAGGAGAGAACTGCTGTGCGTCTGAAGTGATG GCGGAGGGCTTGAAGTTCAAAGATGTGGTCATTTACTTCTCTCAAAAGGAGTGGGAATGCTTGCACTCT GCTCAGAAGGATTTGTACCGAGATGTAATGTTGGAAAATTACGGCAACCTGGTCTTACTGGGGCTTTCT GATACTAAGCCAAATGTGATCTCCTTATTGGAGCAGAAGAAAGAGCCCTGGATGGTTAAGAGGAAGGAG ACAAAAGAATGGTGTCCAGATTGGGAGTTTGGAAGAGAAACCAAGAATTTATCTCCAAAGGAAAACATT TATGAAATTAGATCACCACAACAGGAGAAGGCCAGAGTTATCAGAGAAATCAGATGCCAGGTGGAGAGA CAACAGGGTCATCAGGAGGGACATTTCAGACCAGCTGTAATACCATTTACTTCCATGCAGTGCACAGCC CATAGAGAATATCAGTGGCTTCATACTGGAGAGAAATCCTGTGAATGCAGGAAATGTAAGAATGCTTTT AGGTACCAGTCATGTCCTATTCAACATGAAATAATTCATAATAAGGAAAAAGAACCTGAATGTGGAGAA TGTAGGAAAATCTTTAATAGTGGATCAGACTTGATTAAGCATCAGACGCTTCATGAAAGCAAAAAACAT AGTGAAAATAACAAATGTGCCTTTAATCATGATTCTGGAATTACTCAACCTCAGAGCATTAATACTGGA GAGAAACCTCATAAATGTAAGGAATGTGGGAAAGCCTTTCGTTCCAGCTCACAAATTAGTCAGCATCAG AGGATGCATCTTGGTGAGAAACCCTATAAGTGTAGGGAGTGTGGGAAAGCCTTTCCATCCACTGCACAG CTTAATCTACATCAGAGGATCCATACTGATGAGAAATACTATGAAAGTAAGGCGTGTGGGAAGGCCTTT ACCCGTCCCTCACACCTTTTTCGACATCAAAGAATCCATACGGGTGAGAAACCCCATAAATGTAAGGAA TGTGGAAAGGCTTTTCGTTATGACACACAGCTGAGCCTTCATCAGATAATCCATACTGGTGAAAGACGC TATGAATGCAGGGAGTGTGGAAAGGTGTACAGTTGTGCCTCACAGCTGAGTCTACATCAAAGAATTCAT ACTGGTGAGAAACCCCATGAATGTAAGGAATGTGGGAAAGCCTTTATCTCTGATTCACATCTTATTCGA CATCAGAGTGTCCATACTGGGGAGAAACCCTGTAAGTGTAAGGAATGTGGGAAGTCCTTTCGTCGTGGC TCAGAACTTACCCGACATCAGAGAGCTCATACTGGTGAAAAACCCTATGAGTGTAAGGAATGTGAAAAG GCCTTTACTTGTAGCACAGAACTTGTTCGACATCAAAAAGTTCACACTGGGGAGAGACCCCATAAGTGT AAGGAATGTGGGAAGGCTTTCATTCGAAGGTCAGAACTCACACATCATGAGAGAAGTCACACTGGTGAG AAACCCTACGAGTGTAAGGAGTGTGGGAAGCCCTTTGGTGGTGGCTCAGAACTTAGTTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001204839
Insert Size	1716 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001204839.1
RefSeq Size	2498 bp
RefSeq ORF	1716 bp
Locus ID	374900
UniProt ID	Q3ZCX4
Protein Families	Transcription Factors
MW	66.6 kDa
Gene Summary	Has transcriptional repression activity, partially through the recruitment of the corepressor TRIM28 but has also repression activity independently of this interaction. Essential during embryonic development, where it acts as direct repressor of a placental-specific transcript of IGF2 in early development and regulates convergent extension movements required for axis elongation and tissue morphogenesis in all germ layers. Also important for normal morphogenesis of extraembryonic tissues including the yolk sac, extraembryonic mesoderm and placenta. May enhance proliferation or maintenance of neural stem cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (6) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 6) has a distinct C-terminus and is shorter than isoform 1.

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