KAT7 (NM_001199157) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	HBO1; HBOA; MYST2; ZC2HC7
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331250 representing NM_001199157. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCCGCGAAGGAAGAGGAATGCAGGCAGTAGTTCAGATGGAACCGAAGATTCCGATTTTTCTACAGAT CTCGAGCACACAGACAGTTCAGAAAGTGATGGCACATCCCGACGATCTGCTCGAGTCACCCGCTCCTCA GCCAGGCTAAGCCAGAGTTCTCAAGATTCCAGTCCTGTTCGAAATCTGCAGTCTTTTGGCACTGAGGAG CCTGCTTACTCTACCAGAAGAGTGACCCGTAGTCAGCAGCAGCCTACCCCAGTGACACCGAAAAAATAC CCTCTTCGGCAGACTCGTTCATCTGGTTCAGAAACTGAGCAAGTGGTTGATTTTTCAGATAGAGGACAC CTTACAGGAAAACATGAGAGACATTTCTCCATCTCAGGATGCCCACTGTATCATAACCTCTCAGCTGAC GAATGCAAGGCACCAACGGAGAGGCAGCTTCGATATAAGGAAAAAGTGGCTGAACTCAGGAAGAAAAGA AATTCTGGACTGAGCAAAGAACAGAAAGAGAAATATATGGAACACAGACAGACCTATGGGAACACACGG GAACCTCTTTTAGAAAACCTGACAAGCGAGTATGACTTGGATCTTTTCCGAAGAGCACAAGCCCGGGCT TCAGAGGATTTGGAGAAGTTAAGGCTGCAAGGCCAAATCACAGAGGGAAGCAACATGATTAAAACAATT GCTTTTGGCCGCTATGAGCTTGATACCTGGTATCATTCTCCATATCCTGAAGAATATGCACGGCTGGGA CGTCTCTATATGTGTGAATTCTGTTTAAAATATATGAAGAGCCAAACGATACTCCGCCGGCACATGGCC AAATGTGTGTGGAAACACCCACCTGGTGATGAGATATATCGCAAAGGTTCAATCTCTGTGTTTGAAGTG GATGGCAAGAAAAACAAGATCTACTGCCAAAACCTGTGCCTGTTGGCCAAACTTTTTCTGGACCACAAG ACATTATATTATGATGTGGAGCCCTTCCTGTTCTATGTTATGACAGAGGCGGACAACACTGGCTGTCAC CTGATTGGATATTTTTCTAAGGAAAAGAATTCATTCCTCAACTACAACGTCTCCTGTATCCTTACTATG CCTCAGTACATGAGACAGGGCTATGGCAAGATGCTTATTGATTTCAGTTATTTGCTTTCCAAAGTCGAA GAAAAAGTTGGCTCCCCAGAACGTCCACTCTCAGATCTGGGGCTTATAAGCTATCGCAGTTACTGGAAA GAAGTACTTCTCCGCTACCTGCATAATTTTCAAGGCAAAGAGATTTCTATCAAAGAAATCAGTCAGGAG ACGGCTGTGAATCCTGTGGACATTGTCAGCACTCTGCAAGCCCTTCAGATGCTCAAATACTGGAAGGGA AAACACCTAGTTTTAAAGAGACAGGACCTGATTGATGAGTGGATAGCCAAAGAGGCCAAAAGGTCCAAC TCCAATAAAACCATGGATCCCAGCTGCTTAAAATGGACCCCTCCCAAGGGCACTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001199157
Insert Size	1506 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001199157.1
RefSeq Size	3334 bp
RefSeq ORF	1506 bp
Locus ID	11143
UniProt ID	O95251
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors
MW	58.1 kDa
Gene Summary	The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016] Transcript Variant: This variant (4) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.

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