CFAP410 (NM_001271442) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C21orf2; LRRC76; RDMS; SMDAX; YF5/A2
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330936 representing NM_001271442. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCCCAGCCTGGAGGTGATCACGCTCAGCATCTCCACCCTGGAGCCTGTGAGCCGGTGCCAGCGCCTG AGTGAGCTGTACCTGCGGAGGAACCGCATCCCCAGCCTGGCTGAGCTCTTCTACCTGAAGGGGCTGCCG CGTCTGCGGGTGCTGTGGCTGGCCGAGAACCCGTGCTGCGGCACCAGCCCCCACCGCTACCGCATGACC GTGCTGCGCACCCTGCCGCGCCTACAGAAGCTGGACAACCAGGCTGTGACGGAGGAGGAGCTGTCCCGT GCACTGAGTGAGGGAGAGGAGATCACTGCGGCCCCAGAGAGAGAGGGCACAGGCCACGGCGGCCCCAAG CTATGCTGCACACTGAGCTCCCTCAGCTCCGCTGCTGAGACTGGCCGGGACCCGCTGGACAGCGAGGAG GAGGCAACCGGCGCCCAGGATGAACGTGGCCTGAAGCCGCCTTCCCGGGGCCAGTTTCCTTCCCTCTCA GCCAGGGATGCCTCGAGCAGCCACAGGGGCAGGAACGTCCTGACTGCCATCCTGCTGCTGCTGCGGGAG CTGGATGCAGAGGGGCTGGAGGCCGTGCAGCAGACTGTGGGCAGCCGGCTGCAGGCCCTGCGTGGGGAA GAGGTGCAGGAGCACGCCGAGTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001271442
Insert Size	645 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001271442.1
RefSeq Size	2159 bp
RefSeq ORF	645 bp
Locus ID	755
UniProt ID	O43822
MW	23.6 kDa
Gene Summary	Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012] Transcript Variant: This variant (4) has an alternate 5' exon and an additional exon in the 5' region, which cause translation initiation at a downstream AUG, compared to variant 1. The resulting isoform (4, also known as A2) is shorter and lacks a mitochondrial targeting peptide, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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