UGT2A1 (NM_001252275) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	UDPGT2A1
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330282 representing NM_001252275. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTTAAACAACCTTCTGCTGTTCTCCCTTCAGATAAGTCTCATAGGAACCACTCTTGGTGGGAATGTT TTGATTTGGCCAATGGAAGGTAGTCATTGGCTAAATGTTAAGATAATTATAGATGAGCTCATTAAAAAG GAGCATAATGTGACTGTCCTAGTTGCCTCTGGTGCACTTTTCATCACACCAACCTCTAACCCATCTCTG ACATTTGAAATATATAGGGTGCCCTTTGGCAAAGAAAGAATAGAAGGAGTAATTAAGGACTTCGTTTTG ACATGGCTGGAAAATAGACCATCTCCTTCAACCATTTGGAGATTCTATCAGGAGATGGCCAAAGTAATC AAGGACTTCCACATGGTGTCTCAGGAGATCTGTGATGGCGTTCTTAAAAACCAACAGCTGATGGCAAAG CTAAAGAAAAGCAAGTTTGAAGTCCTGGTGTCTGATCCAGTATTTCCTTGTGGCGATATAGTAGCTTTA AAACTTGGAATTCCATTTATGTACTCCTTGAGGTTTTCTCCAGCCTCAACAGTGGAAAAGCACTGTGGG AAGGTACCATACCCTCCTTCCTATGTTCCTGCTGTTTTATCAGAACTCACCGACCAAATGTCTTTCACT GACAGAATAAGAAATTTCATCTCCTACCACCTACAGGACTACATGTTTGAAACTCTTTGGAAATCATGG GATTCATACTATAGTAAAGCTTTAGGTGGACTCTTACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGGAT CTTGGCTCACTGCAACCTCTGCTTCCCGGGTTCAAGCGATTCTCCCGCCTCAGCCTCCATTGTAGTTGG GATTACAGGCTGCCAGCAGGAAGACCCACTACGTTATGTGAGACTATGGGGAAAGCTGAAATTTGGTTA ATCCGAACATATTGGGATTTTGAATTTCCTCGTCCATACTTACCTAATTTTGAGTTTGTTGGAGGATTG CACTGCAAACCTGCCAAACCTTTACCTAAGGTTTTATGGAGATACAAAGGAAAGAAACCAGCCACATTA GGAAACAATACTCAGCTCTTTGATTGGATACCCCAGAATGATCTTCTTGGACATCCCAAAACCAAAGCT TTTATCACTCATGGTGGAACTAATGGGATCTACGAAGCTATTTACCACGGAGTCCCTATGGTGGGAGTT CCCATGTTTGCTGATCAGCCTGATAACATTGCTCACATGAAGGCCAAAGGAGCAGCTGTGGAAGTGAAC CTAAACACAATGACAAGTGTGGATTTGCTTAGCGCTTTGAGAACAGTCATTAATGAACCTTCTTATAAA GAGAATGCTATGAGGTTATCAAGAATTCACCATGATCAACCTGTAAAGCCCCTGGATCGAGCAGTCTTC TGGATCGAGTTTGTCATGCGCCACAAAGGAGCCAAGCACCTTCGGGTTGCAGCCCATGACCTCACCTGG TTCCAGTACCACTCTTTGGATGTAATTGGGTTCTTGCTGGTCTGTGTGACAACGGCTATATTTTTGGTC ATACAATGTTGTTTGTTTTCCTGTCAAAAATTTGGTAAGATAGGAAAGAAGAAAAAAAGAGAATAG
Restriction Sites	SgfI-MluI
ACCN	NM_001252275
Insert Size	1584 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001252275.1
RefSeq Size	2656 bp
RefSeq ORF	1584 bp
Locus ID	10941
UniProt ID	Q9Y4X1
Protein Families	Transmembrane
Protein Pathways	Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism
MW	60 kDa
Gene Summary	The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (3) lacks an alternate in-frame exon but instead contains a different in-frame exon in the central coding region, compared to variant 2. The encoded isoform (3) is shorter than isoform 2.

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