STAT4 (NM_001243835) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	SLEB11
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330191 representing NM_001243835. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTCTCAGTGGAATCAAGTCCAACAGTTAGAAATCAAGTTTTTGGAGCAGGTGGATCAATTCTATGAT GACAACTTTCCCATGGAAATTCGGCATCTGTTGGCCCAATGGATTGAAAATCAAGACTGGGAGGCAGCT TCTAACAATGAAACCATGGCAACGATTCTTCTTCAAAACTTGTTAATACAACTGGATGAACAGTTAGGT CGTGTTTCCAAAGAGAAAAACCTACTCTTGATACACAATCTAAAAAGAATTAGGAAGGTCCTTCAGGGA AAATTTCATGGAAATCCAATGCATGTAGCTGTGGTTATTTCAAACTGTTTAAGGGAAGAGAGGAGAATA TTGGCTGCAGCCAACATGCCTGTCCAGGGGCCTCTAGAGAAATCCTTACAAAGTTCTTCAGTTTCAGAA AGACAGAGGAATGTGGAGCACAAAGTGGCTGCCATTAAAAACAGTGTGCAGATGACAGAACAAGATACC AAATACTTAGAAGATCTGCAAGACGAATTTGACTACAGGTATAAAACAATTCAGACAATGGATCAGAGT GACAAGAATAGTGCCATGGTGAATCAGGAAGTTTTGACACTGCAGGAAATGCTTAACAGCCTCGATTTC AAGAGAAAGGAGGCTCTCAGTAAAATGACCCAAATCATCCATGAGACAGACCTGTTAATGAACACCATG CTCATAGAAGAGCTGCAAGACTGGAAGCGGCGGCAGCAAATCGCCTGCATCGGGGGTCCACTCCACAAT GGGCTCGACCAGCTTCAGAACTGCTTTACACTATTGGCAGAAAGTCTTTTCCAACTGAGAAGGCAATTG GAGAAACTAGAGGAGCAATCTACCAAAATGACATATGAAGGTGATCCCATTCCAATGCAAAGAACTCAC ATGCTAGAAAGAGTCACCTTCTTGATCTACAACCTTTTCAAGAACTCATTTGTGGTTGAGCGACAGCCA TGTATGCCAACCCACCCTCAGAGGCCGTTGGTACTTAAAACCCTAATTCAGTTCACTGTAAAACTAAGG CTACTAATAAAATTGCCAGAACTAAACTATCAGGTAAAGGTTAAGGCATCAATTGACAAGAATGTTTCA ACTCTAAGCAACCGAAGATTTGTACTTTGTGGAACTAATGTCAAAGCCATGTCTATTGAAGAATCTTCC AATGGGAGTCTCTCAGTAGAATTTCGACATTTGCAACCAAAGGAAATGAAGTCCAGTGCTGGAGGTAAA GGAAATGAGGGCTGTCACATGGTGACTGAAGAACTTCATTCCATAACGTTTGAAACACAGATCTGCCTC TATGGCCTGACCATAGATTTGGAGACCAGCTCATTGCCTGTGGTGATGATTTCCAATGTCAGTCAGTTA CCTAATGCTTGGGCATCCATCATTTGGTACAACGTGTCAACCAACGATTCCCAGAACTTGGTTTTCTTT AATAATCCTCCACCTGCCACATTGAGTCAACTACTGGAGGTGATGAGCTGGCAGTTTTCATCGTACGTT GGTCGTGGTCTTAACTCAGATCAACTCCATATGCTGGCAGAGAAGCTTACAGTCCAATCTAGCTACAGT GATGGTCACCTCACCTGGGCCAAGTTCTGCAAGGAACATTTACCTGGTAAATCATTTACCTTTTGGACA TGGCTTGAAGCAATATTGGATCTAATTAAGAAACACATTCTTCCCCTTTGGATTGATGGGTATGTCATG GGCTTTGTTAGCAAAGAGAAGGAACGGCTGTTGCTAAAGGATAAAATGCCTGGCACCTTTTTATTAAGA TTCAGTGAAAGCCATCTCGGAGGAATAACTTTCACCTGGGTGGACCATTCTGAAAGTGGGGAAGTGAGA TTCCACTCTGTAGAACCCTACAATAAAGGCCGGTTGTCTGCTCTGCCATTCGCTGACATCCTGCGAGAC TACAAAGTTATTATGGCTGAAAACATTCCTGAAAACCCTCTGAAGTACCTATATCCTGACATTCCCAAA GACAAAGCCTTCGGTAAACACTACAGCTCTCAGCCTTGCGAAGTTTCAAGACCAACAGAAAGGGGTGAC AAAGGTTATGTTCCTTCTGTTTTTATCCCCATCTCAACAATCCGAAGTGATTCAACAGAGCCACATTCT CCATCAGACCTTCTTCCCATGTCTCCAAGTGTGTATGCGGTGTTGAGAGAAAACCTGAGTCCCACAACA ATTGAAACTGCAATGAAGTCTCCTTATTCTGCTGAATGA
Restriction Sites	SgfI-MluI
ACCN	NM_001243835
Insert Size	2247 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001243835.1
RefSeq Size	2789 bp
RefSeq ORF	2247 bp
Locus ID	6775
UniProt ID	Q14765
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Jak-STAT signaling pathway
MW	85.9 kDa
Gene Summary	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.

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