IL31RA (NM_001242639) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CRL; CRL3; GLM-R; GLMR; GPL; hGLM-R; IL-31RA; PLCA2; PRO21384; zcytoR17
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC329997 representing NM_001242639. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGACATACTGGAGATTAGAGAACATAGCGAAAACTGAACCACCTAAGATTTTCCGTGTGAAACCAGTT TTGGGCATCAAACGAATGATTCAAATTGAATGGATAAAGCCTGAGTTGGCGCCTGTTTCATCTGATTTA AAATACACACTTCGATTCAGGACAGTCAACAGTACCAGCTGGATGGAAGTCAACTTCGCTAAGAACCGT AAGGATAAAAACCAAACGTACAACCTCACGGGGCTGCAGCCTTTTACAGAATATGTCATAGCTCTGCGA TGTGCGGTCAAGGAGTCAAAGTTCTGGAGTGACTGGAGCCAAGAAAAAATGGGAATGACTGAGGAAGAA GCTCCATGTGGCCTGGAACTGTGGAGAGTCCTGAAACCAGCTGAGGCGGATGGAAGAAGGCCAGTGCGG TTGTTATGGAAGAAGGCAAGAGGAGCCCCAGTCCTAGAGAAAACACTTGGCTACAACATATGGTACTAT CCAGAAAGCAACACTAACCTCACAGAAACAATGAACACTACTAACCAGCAGCTTGAACTGCATCTGGGA GGCGAGAGCTTTTGGGTGTCTATGATTTCTTATAATTCTCTTGGGAAGTCTCCAGTGGCCACCCTGAGG ATTCCAGCTATTCAAGAAAAATCATTTCAGTGCATTGAGGTCATGCAGGCCTGCGTTGCTGAGGACCAG CTAGTGGTGAAGTGGCAAAGCTCTGCTCTAGACGTGAACACTTGGATGATTGAATGGTTTCCGGATGTG GACTCAGAGCCCACCACCCTTTCCTGGGAATCTGTGTCTCAGGCCACGAACTGGACGATCCAGCAAGAT AAATTAAAACCTTTCTGGTGCTATAACATCTCTGTGTATCCAATGTTGCATGACAAAGTTGGCGAGCCA TATTCCATCCAGGCTTATGCCAAAGAAGGCGTTCCATCAGAAGGTCCTGAGACCAAGGTGGAGAACATT GGCGTGAAGACGGTCACGATCACATGGAAAGAGATTCCCAAGAGTGAGAGAAAGGGTATCATCTGCAAC TACACCATCTTTTACCAAGCTGAAGGTGGAAAAGGATTCTCCAAGACAGTCAATTCCAGCATCTTGCAG TACGGCCTGGAGTCCCTGAAACGAAAGACCTCTTACATTGTTCAGGTCATGGCCAGCACCAGTGCTGGG GGAACCAACGGGACCAGCATAAATTTCAAGACATTGTCATTCAGTGTCTTTGAGATTATCCTCATAACT TCTCTGATTGGTGGAGGCCTTCTTATTCTCATTATCCTGACAGTGGCATATGGTCTCAAAAAACCCAAC AAATTGACTCATCTGTGTTGGCCCACCGTTCCCAACCCTGCTGAAAGTAGTATAGCCACATGGCATGGA GATGATTTCAAGGATAAGCTAAACCTGAAGGAGTCTGATGACTCTGTGAACACAGAAGACAGGATCTTA AAACCATGTTCCACCCCCAGTGACAAGTTGGTGATTGACAAGTTGGTGGTGAACTTTGGGAATGTTCTG CAAGAAATTTTCACAGATGAAGCCAGAACGGGTCAGGAAAACAATTTAGGAGGGGAAAAGAATGGGTAT GTGACCTGCCCCTTCAGGCCTGATTGTCCCCTGGGGAAAAGTTTTGAGGAGCTCCCAGTTTCACCTGAG ATTCCGCCCAGAAAATCCCAATACCTACGTTCGAGGATGCCAGAGGGGACCCGCCCAGAAGCCAAAGAG CAGCTTCTCTTTTCTGGTCAAAGTTTAGTACCAGATCATCTGTGTGAGGAAGGAGCCCCAAATCCATAT TTGAAAAATTCAGTGACAGCCAGGGAATTTCTTGTGTCTGAAAAACTTCCAGAGCACACCAAGGGAGAA GTCTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001242639
Insert Size	1869 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001242639.1
RefSeq Size	2839 bp
RefSeq ORF	1869 bp
Locus ID	133396
UniProt ID	Q8NI17
Protein Families	Druggable Genome, Transmembrane
MW	70.4 kDa
Gene Summary	The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] Transcript Variant: This variant (5) differs at the 5' end and contains an additional internal exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (5) with a shorter N-terminus compared to isoform 1.

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