IFRD1 (NM_001197080) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	PC4; TIS7
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC329460 representing NM_001197080. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGAGCCATTGCAGTGGTTATAGCGATCCTTCCAGTTTTGCTGAAGATGGACCAGAAGTCCTTGATGAG GAAGGAACTCAAGAAGACCTAGAGTACAAGTTGAAGGGATTAATTGACCTAACCCTGGATAAGAGTGCG AAGACAAGGCAAGCAGCTCTTGAAGGTATTAAAAATGCACTGGCTTCAAAAATGCTGTATGAATTTATT CTGGAAAGGAGAATGACTTTAACTGATAGCATTGAACGCTGCCTGAAAAAAGGTAAGAGTGATGAGCAA CGTGCAGCTGCAGCGTTAGCATCTGTTCTTTGTATTCAGCTGGGCCCTGGAATTGAAAGTGAAGAGATT TTGAAAACTCTTGGACCAATCCTAAAGAAAATCATTTGTGATGGGTCAGCTAGTATGCAGGCTAGGCAA ACTTGTGCAACTTGCTTTGGTGTTTGCTGTTTTATTGCCACAGATGACATTACTGAACTATACTCAACT CTGGAATGTTTGGAAAATATCTTCACTAAATCCTATCTCAAAGAGAAAGACACTACTGTTATTTGCAGC ACTCCTAATACAGTGCTTCATATCAGCTCTCTTCTTGCATGGACACTACTGCTGACCATATGCCCAATC AATGAAGTGAAGAAAAAGCTTGAGATGCATTTCCATAAGCTTCCAAGCCTCCTCTCTTGTGATGATGTA AACATGAGAATAGCTGCTGGTGAATCTTTGGCACTTCTCTTTGAATTGGCCAGAGGAATAGAGAGTGAC TTTTTTTATGAAGACATGGAGTCCTTGACGCAGATGCTTAGGGCCTTGGCAACAGATGGAAATAAACAC CGGGCCAAAGTGGACAAGAGAAAGCAGCGGTCAGTTTTCAGAGATGTCCTGAGGGCAGTGGAGGAACGG GATTTTCCAACAGAAACCATTAAATTTGGTCCTGAACGCATGTATATTGATTGCTGGGTAAAAAAACAC ACCTATGACACCTTTAAGGAGGTTCTTGGATCAGGGATGCAGTACCACTTGCAGTCAAATGAATTCCTT CGAAATGTATTTGAACTTGGACCCCCAGTGATGCTTGATGCTGCAACGCTTAAAACGATGAAGATTTCT CGTTTCGAAAGGCATTTATATAACTCTGCAGCCTTCAAAGCTCGAACCAAAGCTAGAAGCAAATGTCGA GATAAGAGAGCAGATGTTGGAGAATTCTTCTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001197080
Insert Size	1206 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001197080.1
RefSeq Size	3239 bp
RefSeq ORF	1206 bp
Locus ID	3475
UniProt ID	O00458
MW	45.3 kDa
Gene Summary	This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010] Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Both variant 3 and 4 encode the same isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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