DMT1 (SLC11A2) (NM_001174126) Human Untagged Clone
CAT#: SC328927
SLC11A2 (untagged)-Human solute carrier family 11 (proton-coupled divalent metal ion transporters) member 2 (SLC11A2) transcript variant 2
CNY 9,120.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | AHMIO1; DCT1; DMT1; NRAMP2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_001174126 edited
ATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGGAG TCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCT GGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAG GAGTACTCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCACCGGACCAGGTTTTCTTATG AGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCT GGATTTAAGTTGCTCTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGG CTTGCAGCTAGACTGGGAGTGGTTACTGGGCTGCATCTTGCTGAAGTATGTCACCGTCAG TATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCA GACATGCAAGAAGTCATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATT CCTCTGTGGGGTGGCGTTCTCATCACCATTGCAGATACTTTTGTATTTCTCTTCTTGGAC AAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACTATTATGGCCCTC ACATTTGGATATGAGTATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATG TTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGAACAGGCTGTGGGCATCGTG GGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGACAG GTAAACCGGAACAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCC TGCATTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGTTGTCTCAGTCTTTGCTGAA GCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTCCT CATGCTGGCCTCTTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGT GTTGTGCTGGGATGTTACTTTGGGCCTGCTGCACTCTACATTTGGGCAGTGGGGATCCTG GCTGCAGGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGGGA TTCCTGAACCTAAAGTGGTCACGCTTTGCCCGAGTGGTTCTGACTCGCTCTATTGCCATC ATCCCCACTCTGCTTGTTGCTGTCTTCCAAGATGTAGAGCATCTAACAGGGATGAATGAC TTTCTGAATGTTCTACAGAGCTTACAGCTTCCCTTTGCTCTCATACCCATCCTCACATTT ACGAGCTTGCGGCCAGTAATGAGTGACTTTGCCAATGGACTAGGCTGGCGGATTGCAGGA GGAATCTTGGTCCTTATCATCTGTTCCATCAATATGTACTTTGTAGTGGTTTATGTCCGG GACCTAGGGCATGTGGCATTATATGTGGTGGCTGCTGTGGTCAGCGTGGCTTATCTGGGC TTTGTGTTCTACTTGGGTTGGCAATGTTTGATTGCACTGGGCATGTCCTTCCTGGACTGT GGGCATACGTGCCATCTGGGATTGACAGCTCAGCCTGAACTCTATCTTCTGAACACCATG GACGCTGACTCACTTGTGTCTAGATGA |
Restriction Sites | Please inquire |
ACCN | NM_001174126 |
Insert Size | 1800 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001174126.1, NP_001167597.1 |
RefSeq Size | 3795 bp |
RefSeq ORF | 1707 bp |
Locus ID | 4891 |
UniProt ID | P49281 |
Protein Families | Transmembrane |
Protein Pathways | Lysosome |
Gene Summary | This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010] Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and in the 3' UTR and coding region compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Isoform 2 lacks the iron responsive element (IRE) found in isoform 1. Both variants 2 and 3 encode isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC230289 | SLC11A2 (Myc-DDK-tagged)-Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), transcript variant 2 |
CNY 6,344.00 |
|
RC230289L3 | Lenti-ORF clone of SLC11A2 (Myc-DDK-tagged)-Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), transcript variant 2 |
CNY 6,460.00 |
|
RC230289L4 | Lenti-ORF clone of SLC11A2 (mGFP-tagged)-Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), transcript variant 2 |
CNY 6,460.00 |
|
RG230289 | SLC11A2 (tGFP-tagged) - Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), transcript variant 2 |
CNY 7,944.00 |