HPD (NM_001171993) Human Untagged Clone
CAT#: SC328566
HPD (untagged)-Human 4-hydroxyphenylpyruvate dioxygenase (HPD) transcript variant 2
CNY 7,220.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | 4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC328566 representing NM_001171993.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGCTTTGAACCTCTAGCCTACAGGGGCCTGGAGACCGGTTCCCGGGAGGTGGTCAGCCATGTAATC AAACAAGGGAAGATTGTGTTTGTCCTCTCCTCAGCGCTCAACCCCTGGAACAAAGAGATGGGCGATCAC CTGGTGAAACACGGTGACGGAGTGAAGGACATTGCGTTCGAGGTGGAAGATTGTGACTACATCGTGCAG AAAGCACGGGAACGGGGCGCCAAAATCATGCGGGAGCCCTGGGTAGAGCAAGACAAGTTTGGGAAGGTG AAGTTTGCTGTGCTGCAGACGTATGGGGACACCACACACACCCTGGTGGAGAAGATGAACTACATCGGC CAATTCTTGCCTGGATATGAGGCCCCAGCGTTCATGGACCCCCTACTTCCTAAACTGCCCAAATGCAGT CTGGAGATGATCGACCACATTGTGGGAAACCAGCCTGATCAGGAGATGGTGTCCGCCTCCGAATGGTAC CTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCT CTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTC AAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCC TCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGAT GCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAA CCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCC GGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATG GAGACCAATGGGGTGGTGCCCGGCATGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001171993 |
Insert Size | 1065 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001171993.1 |
RefSeq Size | 1916 bp |
RefSeq ORF | 1065 bp |
Locus ID | 3242 |
UniProt ID | P32754 |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis |
MW | 40.5 kDa |
Gene Summary | The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. |
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC229928 | HPD (Myc-DDK-tagged)-Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2 |
CNY 5,488.00 |
|
RC229928L1 | Lenti ORF clone of Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC229928L2 | Lenti ORF clone of Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
RC229928L3 | Lenti ORF clone of Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC229928L4 | Lenti ORF clone of Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RG229928 | HPD (tGFP-tagged) - Human 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2 |
CNY 4,370.00 |