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PLEKHN1 (NM_001160184) Human Untagged Clone
CAT＃: SC327601
PLEKHN1 (untagged)-Human pleckstrin homology domain containing family N member 1 (PLEKHN1) transcript variant 2
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLPABP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001160184, the custom clone sequence may differ by one or more nucleotides
ATGGGGAACAGCCACTGTGTCCCTCAGGCCCCCAGGAGGCTCCGGGCCTCCTTCTCCAGA AAGCCCTCGCTGAAGGGAAACAGAGAGGACAGCGCGCGGATGTCGGCCGGCCTGCCGGGC CCCGAGGCTGCTCGAAGCGGGGACGCCGCCGCCAACAAGCTCTTCCACTACATCCCGGGC ACGGACATCCTGGACCTGGAGAACCAGCGAGAAAACCTGGAGCAGCCATTCCTGAGTGTG TTCAAGAAGGGGCGGCGGAGGGTGCCTGTGAGGAACCTGGGAAAAGTTGTGCATTACGCC AAGGTCCAGCTGCGGTTCCAGCACAGCCAGGATGTCAGCGACTGCTACCTGGAGCTATTC CCCGCCCACCTGTACTTCCAGGCCCACGGCTCGGAAGGACTCACATTTCAGGGGCTGTTA CCGCTGACGGAGCTGAGTGTCTGCCCGCTCGAGGGGTCCCGAGAGCACGCCTTCCAGATC ACAGGCCCACTGCCCGCACCCCTCCTGGTGCTCTGCCCCAGCCGGGCCGAGCTGGACCGC TGGCTTTACCACCTGGAGAAGCAGACGGCCCTCCTCGGGGGGCCGCGGCGCTGCCACTCG GCACCCCCACAGGGGTCCTGCGGAGACGAACTCCCCTGGACTTTGCAGCGCCGTCTAACC CGGCTGCGGACGGCGTCAGGGCACGAACCCGGCGGCAGTGCTGTCTGTGCCTCGAGGGTC AAGCTGCAGCACCTGCCCGCACAGGAGCAGTGGGACCGGCTCTTGGTCCTGTACCCAACG TCCTTGGCCATTTTCTCCGAGGAGCTGGACGGGCTTTGCTTCAAGGGGGAGCTCCCACTC CGTGCCGTCCACATCAACCTGGAGGAGAAGGAGAAGCAGATCCGCTCCTTCCTGATTGAA GGCCCCCTCATCAACACCATCCGCGTGGTGTGCGCCAGCTACGAGGACTACGGTCACTGG CTGCTGTGCCTTCGCGCTGTCACCCACAGGGAGGGGGCCCCGCCGCTGCCTGGTGCCGAG AGCTTCCCAGGGTCGCAGGTTATGGGCAGTGGCCGAGGCTCACTCTCCTCAGGCGGACAG ACCAGCTGGGACTCGGGGTGCTTGGCGCCCCCCTCCACCCGCACCAGCCACTCCCTGCCT GAGTCCTCAGTGCCATCCACCGTGGGCTGCTCCTCCCAGCACACACCGCTGCACAGGCTG AGCCTGGAGAGCAGCCCAGATGCCCCTGACCACACTTCGGAAACATCACACTCGCCCCTC TATGCCGACCCCTACACACCACCCGCCACCTCCCACCGCAGGGTCACAGATGTCCGGGGC CTGGAGGAGTTCCTCAGTGCCATGCAGAGTGCACGTGGACCCACGCCCTCGAGCCCACTC CCCTCGGTGCCTGTGTCTGTGCCTGCCTCTGACCCTCGCTCCTGCTCCTCCGGCCCCGCT GGCCCCTACTTGCTCTCCAAGAAGGGAGCCCTGCAGTCCAGAGCCGCTCAGAGACACCGG GGCTCAGCCAAGGATGGGGGGCCGCAGCCCCCAGACGCCCCTCAGCTTGTCTCCTCTGCC AGGGAAGGTTCGCCCGAACCCTGGCTGCCTCTGACAGATGGTCGGTCCCCCAGGAGGAGC CGGGACCCCGGCTACGACCACCTCTGGGACGAGACTTTGTCTTCCTCCCACCAGAAGTGC CCCCAGCTTGGAGGGCCTGAGGCCAGTGGGGGGCTTGTGCAGTGGATC |
| Restriction Sites | Please inquire |
| ACCN | NM_001160184 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001160184.1, NP_001153656.1 |
| RefSeq Size | 2299 bp |
| RefSeq ORF | 1731 bp |
| Locus ID | 84069 |
| UniProt ID | Q494U1 |
| Gene Summary | Controls the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR, in cooperation with the RNA stabilizer ELAVL1 (PubMed:29180010). Decreases the stability of the leptin mRNA by antagonizing the function of ELAVL1 by inducing its atypical recruitment from the nucleus to the cytosol (By similarity). Binds to cardiolipin (CL), phosphatidic acid (PA), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylserine (PS) (PubMed:18191643). Promotes apoptosis by enhancing BAX-BAK hetro-oligomerization via interaction with BID in colon cancer cells (PubMed:29531808) (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform b which is shorter than isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228966 | PLEKHN1 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 2 |
CNY 3,990.00 |
|
| RC228966L3 | Lenti-ORF clone of PLEKHN1 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 2 |
CNY 5,890.00 |
|
| RC228966L4 | Lenti-ORF clone of PLEKHN1 (mGFP-tagged)-Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 2 |
CNY 5,890.00 |
|
| RG228966 | PLEKHN1 (tGFP-tagged) - Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 2 |
CNY 4,370.00 |
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