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Slingshot homolog 1 (SSH1) (NM_001161331) Human Untagged Clone
CAT＃: SC327181
SSH1 (untagged)-Human slingshot homolog 1 (Drosophila) (SSH1) transcript variant 3
CNY 13,590.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SSH1L |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001161331, the custom clone sequence may differ by one or more nucleotides
ATGGCCAGAGCTCGGAGGGCAGTTGTAGGGAGCGTTAGAGATGTGAGCACTGCAGCCACG AACCTCTTTTATTTTACCGACTTCTGCATCTTCCTTCAGCCAACCCACTGCTTCTGCTGT CCAGAGGTTTCCAGCTCAAATTACTTAAGTGAGAGCTTTTTCATGGTGAAAGGCGCAGCC CTCTTCTTACAACAGGGAAGCAGCCCTCAAGGCCAGCGGAGTCTTCAGCACCCCCACAAG CATGCAGGTGATCTGCCTCAACATCTTCAGGTGATGATCAACCTTCTGCGTTGCGAAGAC AGAATCAAGCTGGCAGTGCGCCTGGAGAGCGCCTGGGCGGACCGGGTCCGGTACATGGTG GTGGTGTACAGCAGCGGGCGCCAGGACACCGAGGAGAATATCTTGCTGGGAGTGGACTTT TCCAGTAAGGAAAGTAAAAGCTGCACCATTGGGATGGTTCTCCGACTGTGGAGCGACACG AAAATCCACCTTGATGGAGATGGTGGGTTCAGCGTGAGCACAGCAGGAAGGATGCACATA TTTAAGCCTGTGTCTGTCCAGGCCATGTGGTCTGCCCTGCAGGTGCTTCACAAGGCCTGC GAAGTGGCCCGGAGGCACAACTACTTCCCCGGGGGTGTAGCTCTCATCTGGGCTACCTAC TATGAGAGCTGCATCAGCTCCGAGCAGAGCTGCATCAACGAGTGGAACGCCATGCAGGAC CTGGAGTCTACGCGGCCCGACTCCCCCGCGCTATTTGTGGACAAGCCCACTGAAGGGGAA AGGACCGAGCGCCTCATCAAAGCCAAGCTCCGAAGCATCATGATGAGCCAGGATCTAGAA AATGTGACTTCCAAAGAGATTCGTAATGAATTAGAGAAACAGATGAATTGTAACTTGAAG GAACTCAAGGAATTTATAGACAATGAGATGCTACTTATCTTGGGACAGATGGACAAGCCC TCCCTTATCTTCGATCATCTTTATCTCGGCTCTGAATGGAATGCATCCAATCTGGAGGAA CTGCAGGGCTCAGGGGTTGATTACATTTTAAATGTTACCAGAGAAATCGATAATTTTTTT CCTGGCTTATTTGCATATCATAACATCCGAGTCTACGATGAAGAGACCACAGACCTCCTC GCCCACTGGAATGAAGCGTATCATTTTATAAACAAAGCGAAGAGGAACCATTCCAAGTGC CTGGTGCATTGCAAAATGGGCGTGAGTCGCTCGGCCTCCACAGTCATAGCCTATGCAATG AAGGAATTCGGCTGGCCTCTGGAAAAAGCATATAACTATGTAAAGCAGAAGCGCAGCATC ACGCGCCCCAACGCGGGCTTTATGAGGCAGCTGTCTGAGTATGAAGGCATCTTGGATGCA AGCAAACAGCGGCACAACAAGCTGTGGCGTCAGCAGACAGACAGCAGCCTCCAGCAGCCT GTGGATGACCCTGCAGGACCTGGCGACTTCTTGCCAGAGACCCCAGATGGCACCCCGGAA AGCCAGCTGCCCTTCTTGGATGATGCCGCCCAGCCCGGCTTAGGGCCCCCCCTCCCCTGC TGTTTCCGGCGACTCTCAGACCCCCTTCTGCCTTCCCCTGAGGATGAAACTGGCAGCTTG GTCCACCTGGAGGATCCGGAGAGGGAGGCTCTGTTGGAGGAAGCTGCTCCACCTGCAGAG GTGCACAGGCCGGCCAGACAGCCCCAGCAAGGTTCCGGACTCTGTGAGAAGGATGTGAAG AAGAAACTAGAGTTTGGGAGTCCCAAAGGTCGGAGCGGCTCCTTGCTGCAGGTGGAGGAG ACGGAAAGGGAGGAGGGCCTGGGAGCAGGGAGGTGGGGGCAGCTTCCAACCCAGCTCGAT CAAAACCTGCTCAACTCGGAGAACCTAAACAACAACAGCAAGAGGAGCTGTCCCAACGGC ATGGAGGTAGGCAGAGCCCGGCCTGCAGGGTGGCACACCCCATCCCTTCCATCCCACTCT AATTGGCCTACCTCAGCCTCTGTAGTAGGGACTACAGGCACCCGCCACCACACCCAGCTG ATTTTTTTCTATTGTCTCCTCTGGGCCCCCAGCTCCCATCTCCAGGGACCTGAGGGTTCT TTCACAGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_001161331 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001161331.1, NP_001154803.1 |
| RefSeq Size | 2459 bp |
| RefSeq ORF | 2112 bp |
| Locus ID | 54434 |
| UniProt ID | Q8WYL5 |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Regulation of actin cytoskeleton |
| Gene Summary | The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (3) contains an alternative 5' terminal exon, and differs at the 3' end compared to variant 1. This results in a shorter isoform (3) with distinct N- and C-termini compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228546 | SSH1 (Myc-DDK-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 3 |
CNY 7,410.00 |
|
| RC228546L3 | Lenti-ORF clone of SSH1 (Myc-DDK-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 3 |
CNY 9,310.00 |
|
| RC228546L4 | Lenti-ORF clone of SSH1 (mGFP-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 3 |
CNY 9,310.00 |
|
| RG228546 | SSH1 (tGFP-tagged) - Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 3 |
CNY 8,170.00 |
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