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MSL2L1 (MSL2) (NM_001145417) Human Untagged Clone
CAT＃: SC326485
MSL2 (untagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2, mRNA
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MSL-2; MSL2L1; RNF184 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001145417, the custom clone sequence may differ by one or more nucleotides
ATGATGATGAAACCTTCCTGTAGCTGGTGCAAAGACTATGAGCAGTTTGAGGAAAACAAG CAGTTAAGCATCCTAGTGAACTGCTACAAAAAACTATGCGAGTATATAACACAGACTACA CTGGCACGGGATATAATAGAAGCAGTTGACTGTTCTTCTGATATTTTGGCTTTGCTTAAT GATGGATCATTGTTTTGTGAGGAGACAGAAAAACCCTCAGATTCATCCTTTACTTTGTGT TTGACACATTCCCCTTTACCTTCAACCTCAGAACCCACAACTGATCCTCAAGCTAGTTTA TCTCCAATGTCTGAAAGCACCCTCAGCATTGCTATTGGCAGTTCTGTTATCAATGGTTTG CCTACTTATAATGGGCTTTCAATAGATAGATTTGGTATAAATATTCCTTCACCTGAACAT TCAAATACGATTGACGTATGTAATACTGTTGACATAAAAACTGAGGATCTGTCTGACAGC CTGCCACCCGTTTGTGACACAGTAGCCACTGACTTATGTTCCACAGGCATTGATATCTGC AGTTTCAGTGAAGATATAAAACCTGGAGACTCTCTGTTACTGAGTGTTGAGGAAGTACTC CGCAGCTTAGAAACTGTTTCAAATACAGAGGTCTGTTGCCCTAATTTGCAGCCGAACTTG GAAGCCACTGTATCCAATGGACCTTTTCTGCAGCTTTCTTCCCAGTCTCTTAGCCATAAT GTTTTTATGTCCACCAGTCCTGCACTTCATGGGTTATCATGTACAGCAGCAACTCCGAAG ATAGCAAAATTGAATAGAAAACGATCCAGATCAGAGAGTGACAGTGAGAAAGTTCAGCCA CTTCCAATTTCTACCATTATCCGAGGCCCAACACTGGGGGCATCTGCTCCTGTGACAGTG AAACGGGAGAGCAAAATTTCTCTTCAACCTATAGCAACTGTTCCCAATGGAGGCACAACA CCTAAAATCAGCAAAACTGTACTTTTATCTACTAAAAGCATGAAAAAGAGTCATGAACAT GGATCCAAGAAATCTCACTCTAAAACCAAGCCAGGTATTCTTAAAAAAGACAAAGCAGTA AAGGAAAAGATTCCTAGTCATCATTTTATGCCAGGAAGTCCTACCAAGACTGTGTACAAA AAACCCCAGGAAAAGAAAGGGTGTAAATGTGGGCGTGCTACTCAAAATCCAAGTGTTCTT ACATGCCGAGGCCAACGCTGCCCTTGCTACTCTAACCGCAAAGCCTGCTTAGATTGTATA TGTCGTGGCTGCCAAAACTCCTATATGGCCAATGGGGAGAAGAAGCTGGAGGCATTTGCC GTGCCAGAAAAGGCCTTGGAGCAGACCAGGCTCACTTTGGGCATTAACGTGACTAGCATT GCTGTGCGTAACGCTAGTACCAGCACCAGTGTAATAAATGTCACAGGGTCCCCAGTAACG ACGTTTTTAGCTGCCAGTACACATGATGATAAAAGTTTGGATGAAGCTATAGACATGAGA TTCGACTGT |
| Restriction Sites | Please inquire |
| ACCN | NM_001145417 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001145417.1, NP_001138889.1 |
| RefSeq Size | 3895 bp |
| RefSeq ORF | 1512 bp |
| Locus ID | 55167 |
| UniProt ID | Q9HCI7 |
| Protein Families | Druggable Genome |
| Gene Summary | Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate 5' end exon, therefore, has a different 5' UTR compared to transcript variant 1. This results in translation initiation from an in-frame downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226663 | MSL2 (Myc-DDK-tagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 |
CNY 5,800.00 |
|
| RC226663L3 | Lenti-ORF clone of MSL2 (Myc-DDK-tagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 |
CNY 7,700.00 |
|
| RC226663L4 | Lenti-ORF clone of MSL2 (mGFP-tagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 |
CNY 7,700.00 |
|
| RG226663 | MSL2 (tGFP-tagged) - Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 |
CNY 6,370.00 |
