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FAM178A (SLF2) (NM_001136123) Human Untagged Clone
CAT＃: SC326351
FAM178A (untagged)-Human family with sequence similarity 178, member A (FAM178A), transcript variant 2
CNY 22,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C10orf6; FAM178A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC326351 representing NM_001136123.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACAAGGCGCTGCATGCCCGCTAGGCCAGGTTTCCCCTCATCCCCAGCCCCGGGGTCGTCGCCCCCG CGCTGCCATCTGAGACCCGGTAGTACCGCCCATGCTGCAGCGGGAAAGAGAACAGAGAGTCCTGGGGAC AGGAAGCAGTCAATTATAGATTTCTTCAAACCAGCTTCAAAACAAGACAGACACATGTTGGATTCACCA CAAAAATCAAACATCAAATATGGAGGAAGTAGATTGTCTATCACTGGGACAGAGCAGTTTGAAAGGAAA CTATCCTCACCAAAAGAATCTAAACCCAAAAGGGTGCCACCAGAAAAGAGCCCTATTATAGAAGCTTTC ATGAAAGGTGTTAAAGAGCACCATGAAGATCATGGTATACATGAGTCACGTCGGCCTTGTCTGTCACTA GCCTCCAAATATTTAGCCAAAGGAACAAATATCTATGTTCCTTCTTCATATCACTTGCCAAAGGAGATG AAGTCACTAAAGAAAAAACATCGATCCCCAGAGAGAAGGAAGTCACTATTCATTCATGAAAATAATGAG AAGAATGATAGAGATCGAGGCAAAACCAATGCAGACTCCAAAAAGCAGACCACAGTGGCAGAAGCTGAC ATCTTCAATAACAGCTCCAGAAGCCTTAGCAGCAGGAGCAGCCTGTCCAGGCACCACCCGGAAGAAAGC CCACTGGGAGCTAAATTCCAGTTGTCACTAGCTTCTTACTGCAGAGAACGAGAACTAAAGAGGTTGAGA AAGGAGCAAATGGAGCAGAGAATCAACTCCGAGAATTCTTTCTCAGAAGCAAGCAGTCTTTCCTTAAAA TCTAGTATAGAAAGAAAATATAAACCAAGGCAGGAACAAAGGAAACAGAATGACATCATACCTGGAAAA AATAATCTGTCAAATGTGGAAAATGGACATCTCTCAAGAAAAAGATCCTCTTCTGATTCATGGGAACCT ACTTCAGCAGGCTCTAAGCAGAATAAATTCCCTGAAAAAAGAAAAAGGAACTCTGTGGACTCAGATCTG AAAAGCACAAGAGAATCTATGATACCAAAAGCAAGAGAGTCCTTCCTTGAGAAGCGTCCTGATGGACCA CATCAGAAAGAAAAATTTATAAAACATATTGCACTGAAGACACCTGGTGATGTGTTGCGCTTAGAAGAT ATATCCAAGGAACCGAGTGATGAAACTGATGGCTCTTCTGCAGGCTTGGCACCTTCAAATTCTGGCAAT TCTGGCCACCATTCTACCAGGAATAGTGACCAAATCCAAGTGGCAGGTACCAAGGAGACTAAGATGCAG AAACCCCACTTACCTTTATCTCAGGAAAAGTCTGCAATTAAAAAAGCTAGCAACCTTCAGAAAAATAAA ACCGCTAGCTCCACGACAAAGGAGAAGGAGACAAAACTACCTTTACTTTCCCGTGTTCCAAGTGCTGGT TCCTCTCTAGTACCATTAAATGCTAAAAATTGTGCTCTTCCAGTTTCTAAAAAAGATAAAGAGCGTTCC TCATCTAAAGAATGTTCTGGGCATTCTACAGAATCCACCAAACACAAGGAACACAAAGCAAAGACTAAT AAGGCCGATTCTAATGTATCTTCAGGGAAAATTTCTGGGGGACCTTTGCGCTCAGAATATGGCACTCCT ACAAAGTCTCCCCCTGCTGCTTTGGAAGTTGTGCCATGTATCCCAAGCCCTGCAGCACCTTCAGATAAA GCCCCTTCAGAAGGAGAGAGTTCAGGAAATTCCAATGCAGGTAGCAGTGCACTGAAAAGAAAACTAAGG GGTGATTTTGATAGTGATGAAGAAAGTTTAGGTTACAACCTAGACAGTGATGAGGAAGAGGAAACATTA AAGTCACTGGAAGAAATAATGGCTTTGAACTTCAATCAGACTCCTGCAGCTACAGGAAAGCCTCCTGCT CTTTCCAAGGGGCTTAGATCTCAGTCATCAGACTATACAGGACATGTTCATCCTGGAACTTACACAAAT ACCTTAGAACGTCTAGTGAAGGAAATGGAAGACACACAAAGGCTAGATGAACTGCAGAAGCAACTACAA GAAGACATAAGGCAAGGCCGAGGCATTAAATCCCCAATCAGAATTGGAGAAGAAGACAGTACAGATGAT GAGGATGGCCTCTTAGAAGAGCACAAGGAATTTCTAAAGAAATTTTCAGTTACAATTGATGCTATTCCT GATCATCATCCAGGTGAAGAAATATTTAATTTCCTCAATTCTGGAAAAATTTTCAATCAGTATACCTTG GATTTAAGAGACTCTGGTTTTATTGGACAAAGTGCTGTAGAAAAACTTATTCTTAAATCGGGAAAAACA GATCAGATTTTTTTGACAACACAAGGTTTCCTTACGTCTGCTTATCACTATGTCCAGTGTCCTGTCCCT GTGTTAAAGTGGCTGTTTCGGATGATGTCAGTTCATACAGACTGTATTGTGTCAGTGCAGATTTTAAGT ACATTGATGGAAATAACAATTAGAAATGATACCTTCAGTGACTCACCAGTTTGGCCATGGATCCCATCA TTGTCTGATGTAGCAGCTGTGTTTTTCAATATGGGGATTGATTTTAGATCTTTGTTTCCCCTGGAGAAT CTTCAGCCAGACTTTAATGAAGACTATCTAGTTTCTGAAACACAGACAACATCAAGGGGGAAAGAAAGT GAAGATTCATCTTATAAGCCAATTTTTTCAACACTTCCTGAAACCAACATTTTAAATGTGGTTAAGTTT CTAGGCTTGTGTACATCTATACATCCAGAAGGTTACCAGGATCGTGAAATAATGTTGCTGATTTTAATG TTATTTAAAATGAGTTTGGAAAAACAGCTGAAACAGATTCCTTTAGTAGACTTTCAAAGCCTCCTGATA AACCTGATGAAAAACATCAGAGATTGGAACACAAAGGTGCCTGAACTCTGTCTGGGCATAAATGAACTC TCCAGTCATCCCCACAACCTCCTGTGGTTGGTACAGCTGGTCCCTAATTGGACATCACGTGGAAGGCAA CTGAGACAGTGCCTCAGTCTAGTGATTATTTCAAAGCTTTTGGATGAGAAACACGAAGATGTTCCTAAT GCCAGTAATCTGCAGGTATCAGTCCTACATCGCTATCTTGTGCAGATGAAGCCTTCTGATTTGTTAAAG AAAATGGTCTTGAAGAAAAAGGCTGAACAACCAGATGGCATTATTGATGACAGTCTTCATTTAGAACTT GAAAAGCAGGCATATTACCTGACCTACATTCTTCTTCATTTAGTCGGTGAAGTTAGTTGTTCTCATTCT TTTTCTTCTGGACAACGGAAACACTTTGTGCTACTCTGTGGGGCTTTGGAAAAGCATGTTAAATGTGAT ATTAGGGAAGATGCAAGACTTTTTTACAGAACTAAGGTGAAAGACTTGGTCGCCAGGATACATGGAAAA TGGCAGGAAATAATCCAGAACTGTCGGCCTACTCAGGTGTCATTTTGTTATACAATTTCATGTATTCTT AATAGTTTTGCTGAATGGCACTCTTCATACTGTTTGAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001136123 |
| Insert Size | 3561 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001136123.1 |
| RefSeq Size | 4173 bp |
| RefSeq ORF | 3561 bp |
| Locus ID | 55719 |
| UniProt ID | Q8IX21 |
| MW | 133.4 kDa |
| Gene Summary | Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an exon and differs in the 3' UTR, compared to variant 1. The encoded isoform (2) is longer and has a distinct C-terminus, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227146 | FAM178A (Myc-DDK-tagged)-Human family with sequence similarity 178, member A (FAM178A), transcript variant 2 |
CNY 8,256.00 |
|
| RC227146L1 | Lenti ORF clone of Human family with sequence similarity 178, member A (FAM178A), transcript variant 2, Myc-DDK-tagged |
CNY 14,440.00 |
|
| RC227146L2 | Lenti ORF clone of Human family with sequence similarity 178, member A (FAM178A), transcript variant 2, mGFP tagged |
CNY 14,440.00 |
|
| RC227146L3 | Lenti ORF clone of Human family with sequence similarity 178, member A (FAM178A), transcript variant 2, Myc-DDK-tagged |
CNY 14,440.00 |
|
| RC227146L4 | Lenti ORF clone of Human family with sequence similarity 178, member A (FAM178A), transcript variant 2, mGFP tagged |
CNY 14,440.00 |
|
| RG227146 | FAM178A (tGFP-tagged) - Human family with sequence similarity 178, member A (FAM178A), transcript variant 2 |
CNY 13,780.00 |
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