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Semaphorin 4D (SEMA4D) (NM_001142287) Human Untagged Clone
CAT＃: SC326208
SEMA4D (untagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), transcript variant 2
CNY 14,160.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | A8; BB18; C9orf164; CD100; coll-4; COLL4; GR3; M-sema-G; SEMAJ |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001142287, the custom clone sequence may differ by one or more nucleotides
ATGAGGATGTGCACCCCCATTAGGGGGCTGCTCATGGCCCTTGCAGTGATGTTTGGGACA GCGATGGCATTTGCACCCATACCCCGGATCACCTGGGAGCACAGAGAGGTGCACCTGGTG CAGTTTCATGAGCCAGACATCTACAACTACTCAGCCTTGCTGCTGAGCGAGGACAAGGAC ACCTTGTACATAGGTGCCCGGGAGGCGGTCTTCGCTGTGAACGCACTCAACATCTCCGAG AAGCAGCATGAGGTGTATTGGAAGGTCTCAGAAGACAAAAAAGCAAAATGTGCAGAAAAG GGGAAATCAAAACAGACAGAGTGCCTCAACTACATCCGGGTGCTGCAGCCACTCAGCGCC ACTTCCCTTTACGTGTGTGGGACCAACGCATTCCAGCCGGCCTGTGACCACCTGAACTTA ACATCCTTTAAGTTTCTGGGGAAAAATGAAGATGGCAAAGGAAGATGTCCCTTTGACCCA GCACACAGCTACACATCCGTCATGGTTGATGGAGAACTTTATTCGGGGACGTCGTATAAT TTTTTGGGAAGTGAACCCATCATCTCCCGAAATTCTTCCCACAGTCCTCTGAGGACAGAA TATGCAATCCCTTGGCTGAACGAGCCTAGTTTCGTGTTTGCTGACGTGATCCGAAAAAGC CCAGACAGCCCCGACGGCGAGGATGACAGGGTCTACTTCTTCTTCACGGAGGTGTCTGTG GAGTATGAGTTTGTGTTCAGGGTGCTGATCCCACGGATAGCAAGAGTGTGCAAGGGGGAC CAGGGCGGCCTGAGGACCTTGCAGAAGAAATGGACCTCCTTCCTGAAAGCCCGACTCATC TGCTCCCGGCCAGACAGCGGCTTGGTCTTCAATGTGCTGCGGGATGTCTTCGTGCTCAGG TCCCCGGGCCTGAAGGTGCCTGTGTTCTATGCACTCTTCACCCCACAGCTGAACAACGTG GGGCTGTCGGCAGTGTGCGCCTACAACCTGTCCACAGCCGAGGAGGTCTTCTCCCACGGG AAGTACATGCAGAGCACCACAGTGGAGCAGTCCCACACCAAGTGGGTGCGCTATAATGGC CCGGTACCCAAGCCGCGGCCTGGAGCGTGCATCGACAGCGAGGCACGGGCCGCCAACTAC ACCAGCTCCTTGAATTTGCCAGACAAGACGCTGCAGTTCGTTAAAGACCACCCTTTGATG GATGACTCGGTAACCCCAATAGACAACAGGCCCAGGTTAATCAAGAAAGATGTGAACTAC ACCCAGATCGTGGTGGACCGGACCCAGGCCCTGGATGGGACTGTCTATGATGTCATGTTT GTCAGCACAGACCGGGGAGCTCTGCACAAAGCCATCAGCCTCGAGCACGCTGTTCACATC ATCGAGGAGACCCAGCTCTTCCAGGACTTTGAGCCAGTCCAGACCCTGCTGCTGTCTTCA AAGAAGGGCAACAGGTTTGTCTATGCTGGCTCTAACTCGGGCGTGGTCCAGGCCCCGCTG GCCTTCTGTGGGAAGCACGGCACCTGCGAGGACTGTGTGCTGGCGCGGGACCCCTACTGC GCCTGGAGCCCGCCCACAGCGACCTGCGTGGCTCTGCACCAGACCGAGAGCCCCAGCAGG GGTTTGATTCAGGAGATGAGCGGCGATGCTTCTGTGTGCCCGGCCTCGTCTCCTAAGCCC CTCCCTCCTCCTGGCTCCTCTTCCCTGTCCTGTCTGGGCCATGTGGGGGACAGGAGGCTT TCCTCTCCCTGGACCCCCTGGCCAGCCTCGGGTGCGGGGCCCGACAGCAGCTCGAGGGTC TCCTTGCTGCCGCCCTTCCTGAGTGACCAGGCACAGCACGTGCACGCCCTGGGGAACTTC TACCTCTTCTGCCAGGCCACAGGTCCTGCAGACATTCGCTTTGTCTGGGAGAAGAATGGG CGAGCTCTGGAGACCTGTGTCCCTGTGCAGACCCATGCACTGCCCGATGGCAGGGCCCAT GCACTCAGCTGGCTGCAGGACGCCATCAGGGAAAGCGCTGAGTATCGCTGCTCTGTCCTC TCCTCAGCAGGGAACAAGACTTCGAAGGTGCAGGTTGCTGTGATGAGACCTGAAGTGACC CACCAGGAGAGGTGGACCAGAGAGCTCTCTGCCTGGAGGGCTGTGGCTGGGGAGCACGAC CGGATGATGCAGAGCTGGAGGAAGGCGTGGGAAAGCTGTAGCAAGGACACCCTG |
| Restriction Sites | Please inquire |
| ACCN | NM_001142287 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001142287.1, NP_001135759.1 |
| RefSeq Size | 4417 bp |
| RefSeq ORF | 2217 bp |
| Locus ID | 10507 |
| UniProt ID | Q92854 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Axon guidance |
| Gene Summary | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed:19788569). Promotes the migration of cerebellar granule cells (PubMed:16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed:8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed:16055703).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227403 | SEMA4D (Myc-DDK-tagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), transcript variant 2 |
CNY 5,800.00 |
|
| RC227403L3 | Lenti-ORF clone of SEMA4D (Myc-DDK-tagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), transcript variant 2 |
CNY 7,700.00 |
|
| RC227403L4 | Lenti-ORF clone of SEMA4D (mGFP-tagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), transcript variant 2 |
CNY 7,700.00 |
|
| RG227403 | SEMA4D (tGFP-tagged) - Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), transcript variant 2 |
CNY 6,370.00 |
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