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GGCX (NM_001142269) Human Untagged Clone
CAT＃: SC326185
GGCX (untagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2
CNY 13,490.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | VKCFD1 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001142269, the custom clone sequence may differ by one or more nucleotides
ATGGCGGTGTCTGCCGGGTCCGCGCGGACCTCGCCCAGCTCAGGGTTCTTGATGGTGCTA GACATTCCCCAGGAGCGGGGGCTCAGCTCTCTGGACCGGAAATACCTTGATGGGCTGGAT GTGTGCCGCTTCCCCTTGCTGGATGCCCTACGCCCACTGCCACTTGACTGGATGTATCTT GTCTACACCATCATGTTTCTGGGGGCACTGGGCATGATGCTGGGCCTGTGCTACCGGATA AGCTGTGTGTTATTCCTGCTGCCATACTGGTATGTGTTTCTCCTGGACAAGACATCATGG AACAACCACTCCTATCTGTATGGGTTGTTGGCCTTTCAGCTAACATTCATGGATGCAAAC CACTACTGGTCTGTGGACGGTCTGCTGAATGCCCATAGGAGGAATGCCCACGTGCCCCTT TGGAACTATGCAGTGCTCCGTGGCCAGATCTTCATTGTGTACTTCATTGCGGGTGTGAAA AAGCTGGATGCAGACTGGGTTGAAGGCTATTCCATGGAATATTTGTCCCGGCACTGGCTC TTCAGTCCCTTCAAACTGCTGTTGTCTGAGGAGCTGACTAGCCTGCTGGTCGTGCACTGG GGTGGGCTGCTGCTTGACCTCTCAGCTGGTTTCCTGCTCTTTTTTGATGTCTCAAGATCC ATTGGCCTGTTCTTTGTGTCCTACTTCCACTGCATGAATTCCCAGCTTTTCAGCATTGGT ATGTTCTCCTACGTCATGCTGGCCAGCAGCCCTCTCTTCTGCTCCCCTGAGTGGCCTCGG AAGCTGGTGTCCTACTGCCCCCGAAGGTTGCAACAACTGTTGCCCCTCAAGGCAGCCCCT CAGCCCAGTGTTTCCTGTGTGTATAAGAGGAGCCGGGGCAAAAGTGGCCAGAAGCCAGGG CTGCGCCATCAGCTGGGAGCTGCCTTCACCCTGCTCTACCTCCTGGAGCAGCTATTCCTG CCCTATTCTCATTTTCTCACCCAGGGCTATAACAACTGGACAAATGGGCTGTATGGCTAT TCCTGGGACATGATGGTGCACTCCCGCTCCCACCAGCACGTGAAGATCACCTACCGTGAT GGCCGCACTGGCGAACTGGGCTACCTTAACCCTGGGGTATTTACACAGAGTCGGCGATGG AAGGATCATGCAGACATGCTGAAGCAATATGCCACTTGCCTGAGCCGCCTGCTTCCCAAG TATAATGTCACTGAGCCCCAGATCTACTTTGATATTTGGGTCTCCATCAATGACCGCTTC CAGCAGAGGATTTTTGACCCTCGTGTGGACATCGTGCAGGCCGCTTGGTCACCCTTTCAG CGCACATCCTGGGTGCAACCACTCTTGATGGACCTGTCTCCCTGGAGGGCCAAGTTACAG GAAATCAAGAGCAGCCTAGACAACCACACTGAGGTGGTCTTCATTGCAGATTTCCCTGGA CTGCACTTGGAGAATTTTGTGAGTGAAGACCTGGGCAACACTAGCATCCAGCTGCTGCAG GGGGAAGTGACTGTGGAGCTTGTGGCAGAACAGAAGAACCAGACTCTTCGAGAGGGAGAA AAAATGCAGTTGCCTGCTGGTGAGTACCATAAGGTGTATACGACATCACCTAGCCCTTCT TGCTACATGTACGTCTATGTCAACACTACAGAGCTTGCACTGGAGCAAGACCTGGCATAT CTGCAAGAATTAAAGGAAAAGGTGGAGAATGGAAGTGAAACAGGGCCTCTACCCCCAGAG CTGCAGCCTCTGTTGGAAGGGGAAGTAAAAGGGGGCCCTGAGCCAACACCTCTGGTTCAG ACCTTTCTTAGACGCCAACAAAGGCTCCAGGAGATTGAACGCCGGCGAAATACTCCTTTC CATGAGCGATTCTTCCGCTTCTTGTTGCGAAAGCTCTATGTCTTTCGCCGCAGCTTCCTG ATGACTTGTATCTCACTTCGAAATCTGATATTAGGCCGTCCTTCCCTGGAGCAGCTGGCC CAGGAGGTGACTTATGCAAACTTGAGACCCTTTGAGGCAGTTGGAGAACTGAATCCCTCA AACACGGATTCTTCACATTCTAATCCTCCTGAGTCAAATCCTGATCCTGTCCACTCAGAG TTC |
| Restriction Sites | Please inquire |
| ACCN | NM_001142269 |
| Insert Size | 7444 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001142269.1, NP_001135741.1 |
| RefSeq Size | 7444 bp |
| RefSeq ORF | 2106 bp |
| Locus ID | 2677 |
| UniProt ID | P38435 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226869 | GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 5,800.00 |
|
| RC226869L3 | Lenti-ORF clone of GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 7,700.00 |
|
| RC226869L4 | Lenti-ORF clone of GGCX (mGFP-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 7,700.00 |
|
| RG226869 | GGCX (tGFP-tagged) - Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 6,370.00 |
