FES (NM_001143785) Human Untagged Clone
CAT#: SC326181
FES (untagged)-Human feline sarcoma oncogene (FES), transcript variant 4
CNY 13,400.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | FPS |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC326181 representing NM_001143785.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGCTTCTCTTCCGAGCTGTGCAGCCCCCAGGGCCACGGGGTCCTGCAGCAAATGCAGGAGGCCGAG CTTCGTCTACTGGAGGGCATGAGAAAGTGGATGGCCCAGCGGGTCAAGAGTGACAGGGAGTATGCAGGA CTGCTTCACCACATGTCCCTGCAGGACAGTGGGGGCCAGAGCCGGGCCATCAGCCCTGACAGCCCCATC AGTCAGACCCACAGCCAGGACATTGAGAAGCTGAAGAGCCAGTACCGAGCTCTGGCACGGGACAGTGCC CAAGCCAAGCGCAAGTACCAGGAGGCCAGCAAAGACAAGGACCGTGACAAGGCTAAGGACAAGTATGTG CGCAGCCTGTGGAAGCTCTTTGCTCACCACAACCGCTATGTGCTGGGCGTGCGGGCTGCGCAGCTACAC CACCAGCACCACCACCAGCTCCTGCTGCCCGGCCTGCTGCGGTCACTGCAGGACCTGCACGAGGAGATG GCTTGCATCCTGAAGGAGATCCTGCAGGAATACCTGGAGATTAGCAGCCTGGTGCAGGATGAGGTGGTG GCCATTCACCGGGAGATGGCTGCAGCTGCTGCCCGCATCCAGCCTGAGGCTGAGTACCAAGGCTTCCTG CGACAGTATGGGTCCGCACCTGACGTCCCACCCTGTGTCACGTTCGATGAGTCACTGCTTGAGGAGGGT GAACCGCTGGAGCCTGGGGAGCTCCAGCTGAACGAGCTGACTGTGGAGAGCGTGCAGCACACGCTGACC TCAGTGACAGATGAGCTGGCTGTGGCCACCGAGATGGTGTTCAGGCGGCAGGAGATGGTTACGCAGCTG CAACAGGAGCTCCGGAATGAAGAGGAGAACACCCACCCCCGGGAGCGGGTGCAGCTGCTGGGCAAGAGG CAAGTGCTGCAAGAAGCACTGCAGGGGCTGCAGGTAGCGCTGTGCAGCCAGGCCAAGCTGCAGGCCCAG CAGGAGTTGCTGCAGACCAAGCTGGAGCACCTGGGCCCCGGCGAGCCCCCGCCTGTGCTGCTCCTGCAG GATGACCGCCACTCCACGTCGTCCTCGGAGCAGGAGCGAGAGGGGGGAAGGACACCCACGCTGGAGATC CTTAAGAGCCACATCTCAGGAATCTTCCGCCCCAAGTTCTCGAACCTGTACCGACTGGAAGGGGAAGGC TTTCCTAGCATTCCTTTGCTCATCGACCACCTACTGAGCACCCAGCAGCCCCTCACCAAGAAGAGTGGT GTTGTCCTGCACAGGGCTGTGCCCAAGGACAAGTGGGTGCTGAACCATGAGGACCTGGTGTTGGGTGAG CAGATTGGACGGGGGAACTTTGGCGAAGTGTTCAGCGGACGCCTGCGAGCCGACAACACCCTGGTGGCG GTGAAGTCTTGTCGAGAGACGCTCCCACCTGACCTCAAGGCCAAGTTTCTACAGGAAGCGAGGATCCTG AAGCAGTACAGCCACCCCAACATCGTGCGTCTCATTGGTGTCTGCACCCAGAAGCAGCCCATCTACATC GTCATGGAGCTTGTGCAGGGGGGCGACTTCCTGACCTTCCTCCGCACGGAGGGGGCCCGCCTGCGGGTG AAGACTCTGCTGCAGATGGTGGGGGATGCAGCTGCTGGCATGGAGTACCTGGAGAGCAAGTGCTGCATC CACCGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTCCTGAAGATCAGTGACTTTGGG ATGTCCCGAGAGGAAGCCGATGGGGTCTATGCAGCCTCAGGGGGCCTCAGACAAGTCCCCGTGAAGTGG ACCGCACCTGAGGCCCTTAACTACGGCCGCTACTCCTCCGAAAGCGACGTGTGGAGCTTTGGCATCTTG CTCTGGGAGACCTTCAGCCTGGGGGCCTCCCCCTATCCCAACCTCAGCAATCAGCAGACACGGGAGTTT GTGGAGAAGGGGGGCCGTCTGCCCTGCCCAGAGCTGTGTCCTGATGCCGTGTTCAGGCTCATGGAGCAG TGCTGGGCCTATGAGCCTGGGCAGCGGCCCAGCTTCAGCACCATCTACCAGGAGCTGCAGAGCATCCGA AAGCGGCATCGGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001143785 |
Insert Size | 2085 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001143785.1 |
RefSeq Size | 2422 bp |
RefSeq ORF | 2085 bp |
Locus ID | 2242 |
UniProt ID | P07332 |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Axon guidance |
MW | 78.6 kDa |
Gene Summary | This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009] Transcript Variant: This variant (4) lacks multiple in-frame exons in the coding region, compared to variant 1, and encodes a shorter protein (isoform 4) with an incomplete SH2 domain, compared to isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC226923 | FES (Myc-DDK-tagged)-Human feline sarcoma oncogene (FES), transcript variant 4 |
CNY 5,088.00 |
|
RC226923L3 | Lenti-ORF clone of FES (Myc-DDK-tagged)-Human feline sarcoma oncogene (FES), transcript variant 4 |
CNY 9,220.00 |
|
RC226923L4 | Lenti-ORF clone of FES (mGFP-tagged)-Human feline sarcoma oncogene (FES), transcript variant 4 |
CNY 9,220.00 |
|
RG226923 | FES (tGFP-tagged) - Human feline sarcoma oncogene (FES), transcript variant 4 |
CNY 8,080.00 |